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Image Unavailable-BNC550525-500

Anti-CD63 Mouse Monoclonal Antibody (CF555) [clone: MX-49.129.5]

Fornitore: Biotium
Descrizione: This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

Image Unavailable-BNC400186-100

Anti-CD63 Mouse Monoclonal Antibody (CF640R) [clone: NKI-C3]

Fornitore: Biotium
Descrizione: This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

Image Unavailable-BOSSBS-2675R-A647

Anti-PTPRJ Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-2675R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-2675R-A647
Codice articolo locale: BOSSBS-2675R-A647
Descrizione: a-Fodrin is a universally expressed membrane associated cytoskeletal protein consisting of alpha and beta subunits. The protein is important for maintaining normal membrane structure and supporting cell surface protein function. Alpha Fodrin is one of the important targets cleaved by caspases during apoptosis. The full length 240 kDa protein can be cleaved at several sites within its sequence by activated caspases generating N terminal 150 kDa, C terminal 120 kDa, and 35 kDa major products. Cleavage of alpha Fodrin leads to membrane malfunction and cell shrinkage.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9712R-CY7

Anti-SLC9B2 Rabbit Polyclonal Antibody (Cy7®)

Codice catalogo: (BOSSBS-9712R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-9712R-CY7
Codice articolo locale: BOSSBS-9712R-CY7
Descrizione: Na+/H+ exchangers (NHEs) catalyze the transport of Na+ in exchange for H+ across membranes in organisms and are required for numerous physiological processes. NHEDC2 (Na+/H+ exchanger-like domain-containing protein 2), also known as NHA2, is a 537 amino acid mitochondrial protein. NHEDC2 is involved in organelle volume homeostasis by catalyzing the exchange of protons for Na+ and Li+ across the inner mitochondrial membrane. Found in red blood cells, NHEDC2 is required for bone resorption activity and osteoclast differentiation. As a multi-pass membrane protein, NHEDC2 is expressed as two isoforms produced by alternative splicing events.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9712R-A680

Anti-NHEDC2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-9712R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-9712R-A680
Codice articolo locale: BOSSBS-9712R-A680
Descrizione: Na⁺/H⁺ exchangers (NHEs) catalyse the transport of Na⁺ in exchange for H⁺ across membranes in organisms and are required for numerous physiological processes. NHEDC2 (Na⁺/H⁺ exchanger-like domain-containing protein 2), also known as NHA2, is a 537 amino acid mitochondrial protein. NHEDC2 is involved in organelle volume homeostasis by catalyzing the exchange of protons for Na⁺ and Li⁺ across the inner mitochondrial membrane. Found in red blood cells, NHEDC2 is required for bone resorption activity and osteoclast differentiation. As a multi-pass membrane protein, NHEDC2 is expressed as two isoforms produced by alternative splicing events.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1824R-HRP

Anti-HMP Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Codice catalogo: (BOSSBS-1824R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-1824R-HRP
Codice articolo locale: BOSSBS-1824R-HRP
Descrizione: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:22114354, PubMed:25781180).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1824R-A647

Anti-HMP Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-1824R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-1824R-A647
Codice articolo locale: BOSSBS-1824R-A647
Descrizione: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:22114354, PubMed:25781180).
UOM: 1 * 100 µl
Image Unavailable-514-0739

Cartridge filters, Optimizer® PR 16 and PR 40

Fornitore: ENTEGRIS
Descrizione: The UPE membrane of these filters eliminates pre-wetting, which optimises the full use of the membrane and ensures maximum flow.

Product Image-MILFSLAAR33SB

Millex® MCE MF-Millipore™ Membrane Syringe Filters, Sterile

Fornitore: Merck
Descrizione: Sterile Millex filter units are available in a larger 33 mm housing with MCE membranes.

Image Unavailable-BOSSBS-7744R-A750

Anti-CHMP4B+CHMP4C Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Codice catalogo: (BOSSBS-7744R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-7744R-A750
Codice articolo locale: BOSSBS-7744R-A750
Descrizione: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7744R-A647

Anti-CHMP4B+CHMP4C Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-7744R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-7744R-A647
Codice articolo locale: BOSSBS-7744R-A647
Descrizione: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7744R-A555

Anti-CHMP4B+CHMP4C Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Codice catalogo: (BOSSBS-7744R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-7744R-A555
Codice articolo locale: BOSSBS-7744R-A555
Descrizione: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7744R-A488

Anti-CHMP4B+CHMP4C Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Codice catalogo: (BOSSBS-7744R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-7744R-A488
Codice articolo locale: BOSSBS-7744R-A488
Descrizione: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7744R-FITC

Anti-CHMP4B+CHMP4C Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-7744R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-7744R-FITC
Codice articolo locale: BOSSBS-7744R-FITC
Descrizione: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1564R-CY5.5

Anti-Annexin IV Rabbit Polyclonal Antibody (Cy5.5®)

Codice catalogo: (BOSSBS-1564R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-1564R-CY5.5
Codice articolo locale: BOSSBS-1564R-CY5.5
Descrizione: The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin A4 (ANXA4) belongs to the annexin family of calcium dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane related events along exocytotic and endocytotic pathways. ANXA4 has 45 to 59% identity with other members of its family and shares a similar size and exon intron organization. Isolated from human placenta, ANXA4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANXA4 is almost exclusively expressed in epithelial cells.
UOM: 1 * 100 µl
Image Unavailable-USBIL9190-14B

Anti-Lysosome Associated Membrane Protein 2 Mouse Monoclonal Antibody (Biotin) [clone: 5K77]

Codice catalogo: (USBIL9190-14B)
Fornitore: US Biological
Codice articolo fornitore: L9190-14B
Codice articolo locale: USBIL9190-14B
Descrizione: Anti-Lysosome Associated Membrane Protein 2 Mouse Monoclonal Antibody (Biotin) [clone: 5K77]
UOM: 1 * 100 Tests
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