Hai cercato: 8-(4-Chlorophenylthio)guanosine+3\',5\'-cyclic+Monophosphothioate

Fornitore: ENZO LIFE SCIENCES AG

Descrizione: Potent selective inhibitor of cGMP-dependent protein kinase 1α, 1β and type II. Resistant to mammalian cyclic nucleotide-dependent phosphodiesterases, no metabolic side effects. Significantly more lipophilic and membrane permeant as compared to Rp-cGMPS or Rp-8-Br-cGMPS.

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Codice catalogo: (ENZOBMLCN2060001)

Fornitore: ENZO LIFE SCIENCES AG

Codice articolo fornitore: BMLCN2060001

Codice articolo locale: ENZOBMLCN2060001

Descrizione: A cell-permeable cGMP antagonist which is resistant to hydrolysis by cyclic nucleotide phosphodiesterases (Ki=0.5 µM). No metabolic side effects. Significantly more lipophilic and membrane permeant as compared to Rp-cGMPS or Rp-8-Br-cGMPS

UOM: 1 * 1 mg

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Codice catalogo: (ENZOALX480072M001)

Fornitore: ENZO LIFE SCIENCES AG

Codice articolo fornitore: ALX480072M001

Codice articolo locale: ENZOALX480072M001

Descrizione: Inhibitor of cGMP-dependent protein kinase (PKG) 1α (cGMP antagonist). Resistant against mammalian cyclic nucleotid-dependent phosphodiesterases. No metabolic side effects. Low membrane permeability.

UOM: 1 * 1 mg

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Fornitore: ENZO LIFE SCIENCES AG

Descrizione: Selective activator of cGMP-dependent protein kinase (PKG) Iα, Iβ, and type II as well as of cGMP-gated ion channels.

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Codice catalogo: (ENZOALX480031M005)

Fornitore: ENZO LIFE SCIENCES AG

Codice articolo fornitore: ALX480031M005

Codice articolo locale: ENZOALX480031M005

Descrizione: Activator of PKG and CNG channels.

UOM: 1 * 5 mg

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Fornitore: ENZO LIFE SCIENCES AG

Descrizione: Inhibitor of cAMP-dependent protein kinase (PKA), preferentially binding to type I PKA. Lipophilic analog of Rp-cAMPS. Resistant to mammalian cyclic nucleotide-dependent phosphodiesterases. Significantly more lipophilic and membrane permeant as compared to Rp-cAMPS or 8-Br-cAMP.

New Product

Codice catalogo: (ENZOALX480085M001)

Fornitore: ENZO LIFE SCIENCES AG

Codice articolo fornitore: ALX480085M001

Codice articolo locale: ENZOALX480085M001

Descrizione: Competitive inhibitor of cyclic AMP-dependent protein kinase I and II.Metabolic stability towards mammalian cyclic nucleotide- responsive phosphodiesterases.
Discriminates between protein kinase A (antagonist) and some other cyclic AMP receptors, e.g. channels or CAP 3 (agonist).Membrane-permeant for several systems (for improved permeability more lipophilic analogues e.g. Rp-8-Br-cAMPS are recommended).

UOM: 1 * 1 mg

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Codice catalogo: (ENZOALX480025M001)

Fornitore: ENZO LIFE SCIENCES AG

Codice articolo fornitore: ALX480025M001

Codice articolo locale: ENZOALX480025M001

Descrizione: PKA activator.

UOM: 1 * 1 mg

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Fornitore: ENZO LIFE SCIENCES AG

Descrizione: Specific, potent and membrane permeant activator of the Epac cAMP receptor.

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Fornitore: ENZO LIFE SCIENCES AG

Descrizione: PKA activator.

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Fornitore: Cayman Chemical

Descrizione: 3'3'-cGAMP (sodium salt) ≥98%

Codice catalogo: (BOSSBS-3892R-CY5)

Fornitore: Bioss

Codice articolo fornitore: BS-3892R-CY5

Codice articolo locale: BOSSBS-3892R-CY5

Descrizione: Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-3892R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-3892R-A680

Codice articolo locale: BOSSBS-3892R-A680

Descrizione: Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-13470R-A555)

Fornitore: Bioss

Codice articolo fornitore: BS-13470R-A555

Codice articolo locale: BOSSBS-13470R-A555

Descrizione: Heterotrimeric guanine nucleotide-binding proteins (G proteins) transduce extracellular signals received by transmembrane receptors to effector proteins. Transducin is a guanine nucleotide-binding protein found specifically in rod outer segments, where it mediates activation by rhodopsin of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase. Transducin is also referred to as GMPase. GNGT1 encodes the gamma subunit of transducin (Hurley et al., 1984 [PubMed 6438626]; Scherer et al., 1996 [PubMed 8661128]).[supplied by OMIM, Mar 2008].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-13470R-A647)

Fornitore: Bioss

Codice articolo fornitore: BS-13470R-A647

Codice articolo locale: BOSSBS-13470R-A647

Descrizione: Heterotrimeric guanine nucleotide-binding proteins (G proteins) transduce extracellular signals received by transmembrane receptors to effector proteins. Transducin is a guanine nucleotide-binding protein found specifically in rod outer segments, where it mediates activation by rhodopsin of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase. Transducin is also referred to as GMPase. GNGT1 encodes the gamma subunit of transducin (Hurley et al., 1984 [PubMed 6438626]; Scherer et al., 1996 [PubMed 8661128]).[supplied by OMIM, Mar 2008].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-13470R-CY5)

Fornitore: Bioss

Codice articolo fornitore: BS-13470R-CY5

Codice articolo locale: BOSSBS-13470R-CY5

Descrizione: Heterotrimeric guanine nucleotide-binding proteins (G proteins) transduce extracellular signals received by transmembrane receptors to effector proteins. Transducin is a guanine nucleotide-binding protein found specifically in rod outer segments, where it mediates activation by rhodopsin of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase. Transducin is also referred to as GMPase. GNGT1 encodes the gamma subunit of transducin (Hurley et al., 1984 [PubMed 6438626]; Scherer et al., 1996 [PubMed 8661128]).[supplied by OMIM, Mar 2008].

UOM: 1 * 100 µl

Promo