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Descrizione: Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM].
Codice catalogo: BOSSBS-2652R-A350
UOM: 1 * 100 µl
Codice articolo fornitore: BS-2652R-A350
Codice articolo locale: BOSSBS-2652R-A350
Fornitore: Bioss


Descrizione: Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM].
Codice catalogo: BOSSBS-2652R-HRP
UOM: 1 * 100 µl
Codice articolo fornitore: BS-2652R-HRP
Codice articolo locale: BOSSBS-2652R-HRP
Fornitore: Bioss


Descrizione: Memantine lactose adduct 95%
Codice catalogo: APOSBICL4314-10MG
UOM: 1 * 10 mg
Codice articolo fornitore: BICL4314-10MG
Codice articolo locale: APOSBICL4314-10MG
Fornitore: Apollo Scientific


Descrizione: Pentostatin can inhibit adenosine deaminase irreversibly with Ki of 2.5 pM, as an antineoplastic anti-metabolite used in the treatment of several forms of leukemia.
Codice catalogo: APOSBISN0008-5MG
UOM: 1 * 5 mg
Codice articolo fornitore: BISN0008-5MG
Codice articolo locale: APOSBISN0008-5MG
Fornitore: Apollo Scientific


Descrizione: Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM].
Codice catalogo: BOSSBS-2652R
UOM: 1 * 100 µl
Codice articolo fornitore: BS-2652R
Codice articolo locale: BOSSBS-2652R
Fornitore: Bioss


Descrizione: Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM].
Codice catalogo: BOSSBS-2652R-A555
UOM: 1 * 100 µl
Codice articolo fornitore: BS-2652R-A555
Codice articolo locale: BOSSBS-2652R-A555
Fornitore: Bioss


Descrizione: Reagent for maintaining -SH groups in reduced state.
Codice catalogo: APOSBI8765-10G
UOM: 1 * 10 g
Codice articolo fornitore: BI8765-10G
Codice articolo locale: APOSBI8765-10G
Fornitore: Apollo Scientific


Descrizione: G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G(i) subclass of heteromeric G proteins. Signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. Plays an important role in cell migration, probably via its role in the reorganisation of the actin cytoskeleton and the formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1. Required for normal chemotaxis toward sphingosine 1-phosphate. Required for normal embryonic heart development and normal cardiac morphogenesis. Plays an important role in the regulation of sprouting angiogenesis and vascular maturation. Inhibits sprouting angiogenesis to prevent excessive sprouting during blood vessel development. Required for normal egress of mature T-cells from the thymus into the blood stream and into peripheral lymphoid organs. Plays a role in the migration of osteoclast precursor cells, the regulation of bone mineralisation and bone homeostasis (By similarity). Plays a role in responses to oxidised 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine by pulmonary endothelial cells and in the protection against ventilator-induced lung injury.
Codice catalogo: BOSSBS-7112R-A680
UOM: 1 * 100 µl
Codice articolo fornitore: BS-7112R-A680
Codice articolo locale: BOSSBS-7112R-A680
Fornitore: Bioss


Descrizione: GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.
Codice catalogo: BOSSBS-0136R-CY5
UOM: 1 * 100 µl
Codice articolo fornitore: BS-0136R-CY5
Codice articolo locale: BOSSBS-0136R-CY5
Fornitore: Bioss


Descrizione: GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.
Codice catalogo: BOSSBS-0136R-CY7
UOM: 1 * 100 µl
Codice articolo fornitore: BS-0136R-CY7
Codice articolo locale: BOSSBS-0136R-CY7
Fornitore: Bioss


Descrizione: Fumonisin B2 96+%
Codice catalogo: ACRO328260010
UOM: 1 * 1 mg
Codice articolo fornitore: 328260010
Codice articolo locale: ACRO328260010
Fornitore: Thermo Fisher Scientific

MSDS


Descrizione: GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.
Codice catalogo: BOSSBS-0136R-A488
UOM: 1 * 100 µl
Codice articolo fornitore: BS-0136R-A488
Codice articolo locale: BOSSBS-0136R-A488
Fornitore: Bioss


Descrizione: GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.
Codice catalogo: BOSSBS-0136R-HRP
UOM: 1 * 100 µl
Codice articolo fornitore: BS-0136R-HRP
Codice articolo locale: BOSSBS-0136R-HRP
Fornitore: Bioss


Descrizione: G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G(i) subclass of heteromeric G proteins. Signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. Plays an important role in cell migration, probably via its role in the reorganization of the actin cytoskeleton and the formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1. Required for normal chemotaxis toward sphingosine 1-phosphate. Required for normal embryonic heart development and normal cardiac morphogenesis. Plays an important role in the regulation of sprouting angiogenesis and vascular maturation. Inhibits sprouting angiogenesis to prevent excessive sprouting during blood vessel development. Required for normal egress of mature T-cells from the thymus into the blood stream and into peripheral lymphoid organs. Plays a role in the migration of osteoclast precursor cells, the regulation of bone mineralization and bone homeostasis (By similarity). Plays a role in responses to oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine by pulmonary endothelial cells and in the protection against ventilator-induced lung injury.
Codice catalogo: BOSSBS-7112R-CY5
UOM: 1 * 100 µl
Codice articolo fornitore: BS-7112R-CY5
Codice articolo locale: BOSSBS-7112R-CY5
Fornitore: Bioss


Descrizione: GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.
Codice catalogo: BOSSBS-0136R-CY5.5
UOM: 1 * 100 µl
Codice articolo fornitore: BS-0136R-CY5.5
Codice articolo locale: BOSSBS-0136R-CY5.5
Fornitore: Bioss


Descrizione: FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analog of sphingosine. It is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs.
Codice catalogo: CAYM10008639-5
UOM: 1 * 5 mg
Codice articolo fornitore: 10008639-5
Codice articolo locale: CAYM10008639-5
Fornitore: Cayman Chemical