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Image Unavailable-BOSSBS-12411R-A680

Anti-Prickle Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-12411R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-12411R-A680
Codice articolo locale: BOSSBS-12411R-A680
Descrizione: Prickle1 is an 831 amino acid protein that contains one PET domain and three LIM zinc-binding domains and localizes to the cytoplasm, as well as to the nuclear membrane. Expressed at higher levels in placenta and at lower levels in liver, brain, kidney, lung and pancreas, Prickle1 is thought to function as a nuclear receptor that interacts with NRSF, a silencer protein that binds the DNA sequence element NRSE (neuron-restrictive silencer element). Defects in the gene encoding Prickle1 are associated with autosomal recessive progressive myoclonic epilepsy-1B, which is characterised by quick jerks of the arms, shoulders or legs. The gene encoding Prickle1 maps to human chromosome 12, which encodes over 1100 genes and comprises approximately 4.5% of the human genome.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12411R-A750

Anti-Prickle Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Codice catalogo: (BOSSBS-12411R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-12411R-A750
Codice articolo locale: BOSSBS-12411R-A750
Descrizione: Prickle1 is an 831 amino acid protein that contains one PET domain and three LIM zinc-binding domains and localizes to the cytoplasm, as well as to the nuclear membrane. Expressed at higher levels in placenta and at lower levels in liver, brain, kidney, lung and pancreas, Prickle1 is thought to function as a nuclear receptor that interacts with NRSF, a silencer protein that binds the DNA sequence element NRSE (neuron-restrictive silencer element). Defects in the gene encoding Prickle1 are associated with autosomal recessive progressive myoclonic epilepsy-1B, which is characterised by quick jerks of the arms, shoulders or legs. The gene encoding Prickle1 maps to human chromosome 12, which encodes over 1100 genes and comprises approximately 4.5% of the human genome.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12411R-A647

Anti-Prickle Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-12411R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-12411R-A647
Codice articolo locale: BOSSBS-12411R-A647
Descrizione: Prickle1 is an 831 amino acid protein that contains one PET domain and three LIM zinc-binding domains and localizes to the cytoplasm, as well as to the nuclear membrane. Expressed at higher levels in placenta and at lower levels in liver, brain, kidney, lung and pancreas, Prickle1 is thought to function as a nuclear receptor that interacts with NRSF, a silencer protein that binds the DNA sequence element NRSE (neuron-restrictive silencer element). Defects in the gene encoding Prickle1 are associated with autosomal recessive progressive myoclonic epilepsy-1B, which is characterized by quick jerks of the arms, shoulders or legs. The gene encoding Prickle1 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11589R-A647

Anti-HOXC5 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-11589R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-11589R-A647
Codice articolo locale: BOSSBS-11589R-A647
Descrizione: The Hox homeobox genes encode proteins that are transcriptional regulators with an established role in embryonic development. HoxC5 is a 222 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. Existing as multiple alternatively spliced isoforms, HoxC5 functions as a sequence-specific DNA-binding transcription factor that is part of a regulatory mechanism that provides cells with positional identities during development. The gene encoding HoxC5 maps to a cluster of Hox proteins on chromosome 12 that are essential for morphogenesis. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11451R-CY5

Anti-HSPB2 Rabbit Polyclonal Antibody (Cy5®)

Codice catalogo: (BOSSBS-11451R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-11451R-CY5
Codice articolo locale: BOSSBS-11451R-CY5
Descrizione: Advillin is an 819 amino acid protein that localizes to both the cytoplasm and the cytoskeleton and contains one HP domain and six gelsolin-like repeats. Expressed at high levels in colon and small intestine and at lower levels in uterus, thymus, testis and prostate, advillin functions as a calcium-regulated Actin-binding protein that may be involved in the development of neuronal cells, specifically those that form ganglia. The gene encoding advillin maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11340R-CY5

Anti-CPEB3 Rabbit Polyclonal Antibody (Cy5®)

Codice catalogo: (BOSSBS-11340R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-11340R-CY5
Codice articolo locale: BOSSBS-11340R-CY5
Descrizione: The regulated translation of messenger RNA is essential for cell-cycle progression, establishment of the body plan during early development and modulation of key activities in the central nervous system. Cytoplasmic polyadenylation, one mechanism of controlling translation, is driven by cytoplasmic polyadenylation element binding proteins, called CPEBs. CPEB3 (cytoplasmic polyadenylation element binding protein 3) is a 698 amino acid protein that contains two RNA recognition motif (RRM) domains and, like other CPEB proteins, may play a role in the maturation of the central nervous system. CPEB3 exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11451R-A647

Anti-HSPB2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-11451R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-11451R-A647
Codice articolo locale: BOSSBS-11451R-A647
Descrizione: Advillin is an 819 amino acid protein that localizes to both the cytoplasm and the cytoskeleton and contains one HP domain and six gelsolin-like repeats. Expressed at high levels in colon and small intestine and at lower levels in uterus, thymus, testis and prostate, advillin functions as a calcium-regulated Actin-binding protein that may be involved in the development of neuronal cells, specifically those that form ganglia. The gene encoding advillin maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11451R-A680

Anti-Advillin Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-11451R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-11451R-A680
Codice articolo locale: BOSSBS-11451R-A680
Descrizione: Advillin is an 819 amino acid protein that localizes to both the cytoplasm and the cytoskeleton and contains one HP domain and six gelsolin-like repeats. Expressed at high levels in colon and small intestine and at lower levels in uterus, thymus, testis and prostate, advillin functions as a calcium-regulated Actin-binding protein that may be involved in the development of neuronal cells, specifically those that form ganglia. The gene encoding advillin maps to human chromosome 12, which encodes over 1100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4272R

Anti-CHFR Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-4272R)
Fornitore: Bioss
Codice articolo fornitore: BS-4272R
Codice articolo locale: BOSSBS-4272R
Descrizione: A number of human cancers are sensitive to mitotic stress, implying checkpoint defects. Many proteins that contain forkhead-associated (FHA) domains are cell cycle checkpoints and CHFR is one such protein. It has a FHA and ring finger domain within its N terminus. Within its C terminus, CHFR contains a cysteine-rich region that did not display significant similarity to any protein in the GenBank database, but is highly conserved between humans and mice. It has been concluded that CHFR defines a checkpoint that delays entry into metaphase in response to mitotic stress. It has been found CpG methylation-dependent silencing of CHFR expression occurs in 45% of cancer cell lines, 40% of primary colorectal cancers, 53% of colorectal adenomas, and 30% of primary head and neck cancers.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6300R

Anti-PLXDC2 Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-6300R)
Fornitore: Bioss
Codice articolo fornitore: BS-6300R
Codice articolo locale: BOSSBS-6300R
Descrizione: TEM7R also known as PLXDC2 is a 529 amino acid single-pass type I membrane protein containing one PSI domain and belonging to the plexin family. Localizing to membrane, TEM7R is expressed in endothelial cells of the stroma, as well as in limbs, lung buds, developing heart, spinal cord and dorsal root ganglia. TEM7R interacts with cortactin and may play a role in tumor angiogenesis. Existing as three alternatively spliced isoforms, the gene encoding TEM7R maps to human chromosome 10p12.31. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3800R-A750

Anti-Kappa Light Chain Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Codice catalogo: (BOSSBS-3800R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-3800R-A750
Codice articolo locale: BOSSBS-3800R-A750
Descrizione: Immunoglobulins belong to a group of related glyco proteins which make up 20% of serum proteins. Antigens and immunoglobulins react to confer immunity to individuals. Immunoglobulins have similar structures of two identical heavy chains and two identical light chains. Both the heavy chains and the light chains are divided into constant and variable regions. The constant regions have the same amino acid sequences between all the immunoglobulin classes. The variable regions have approximately 110 amino acids with high sequence variability. The amino acid sequence of the heavy chain determines the class of an immunoglobulin. The five types of immunoglobulin heavy chains are known as: IgG, IgA, IgM, IgD, and IgE. IgG is divided into four subclasses, and IgA is divided into two subclasses. In serum IgA and IgG are monomers with a single 4 polypeptide unit; while, IgM is a pen tamer. IgA may also form polymers. Kappa light chain antibody can be used for the identification of leukaemias, plasmacytomas and certain non Hodgkin's lymphomas. Kappa light chain contains one immunoglobulin like domain. The EU sequence has the INV allotypic marker, Ala 45 and Val 83. The ROY sequence has the INV allotypic marker, Ala 45 and Leu 83.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3800R-HRP

Anti-ZNF211 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Codice catalogo: (BOSSBS-3800R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-3800R-HRP
Codice articolo locale: BOSSBS-3800R-HRP
Descrizione: Immunoglobulins belong to a group of related glyco proteins which make up 20% of serum proteins. Antigens and immunoglobulins react to confer immunity to individuals. Immunoglobulins have similar structures of two identical heavy chains and two identical light chains. Both the heavy chains and the light chains are divided into constant and variable regions. The constant regions have the same amino acid sequences between all the immunoglobulin classes. The variable regions have approximately 110 amino acids with high sequence variability. The amino acid sequence of the heavy chain determines the class of an immunoglobulin. The five types of immunoglobulin heavy chains are known as: IgG, IgA, IgM, IgD, and IgE. IgG is divided into four subclasses, and IgA is divided into two subclasses. In serum IgA and IgG are monomers with a single 4 polypeptide unit; while, IgM is a pen tamer. IgA may also form polymers. Kappa light chain antibody can be used for the identification of leukemias, plasmacytomas and certain non Hodgkin's lymphomas. Kappa light chain contains one immunoglobulin like domain. The EU sequence has the INV allotypic marker, Ala 45 and Val 83. The ROY sequence has the INV allotypic marker, Ala 45 and Leu 83.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3800R-A555

Anti-ZNF211 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Codice catalogo: (BOSSBS-3800R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-3800R-A555
Codice articolo locale: BOSSBS-3800R-A555
Descrizione: Immunoglobulins belong to a group of related glyco proteins which make up 20% of serum proteins. Antigens and immunoglobulins react to confer immunity to individuals. Immunoglobulins have similar structures of two identical heavy chains and two identical light chains. Both the heavy chains and the light chains are divided into constant and variable regions. The constant regions have the same amino acid sequences between all the immunoglobulin classes. The variable regions have approximately 110 amino acids with high sequence variability. The amino acid sequence of the heavy chain determines the class of an immunoglobulin. The five types of immunoglobulin heavy chains are known as: IgG, IgA, IgM, IgD, and IgE. IgG is divided into four subclasses, and IgA is divided into two subclasses. In serum IgA and IgG are monomers with a single 4 polypeptide unit; while, IgM is a pen tamer. IgA may also form polymers. Kappa light chain antibody can be used for the identification of leukemias, plasmacytomas and certain non Hodgkin's lymphomas. Kappa light chain contains one immunoglobulin like domain. The EU sequence has the INV allotypic marker, Ala 45 and Val 83. The ROY sequence has the INV allotypic marker, Ala 45 and Leu 83.
UOM: 1 * 100 µl
Product Image-MLDVFLEX3-R

Microplate readers, multi-mode, FlexStation® 3

Fornitore: Molecular Devices
Descrizione: FlexStation® 3 Benchtop Multi-Mode Microplate Reader combines SpectraMax® M5e Multi-Mode Microplate Reader performance with an integrated 8- or 16-channel pipettor into one compact benchtop reader. The FlexStation 3 Microplate Reader high-efficiency monochromator optics are tunable for absorbance, fluorescence intensity, fluorescence polarisation, and time-resolved fluorescence assays. It also has a dedicated photomultiplier tube for luminescence assays.

Image Unavailable-BOSSBS-12411R-HRP

Anti-Prickle Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Codice catalogo: (BOSSBS-12411R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-12411R-HRP
Codice articolo locale: BOSSBS-12411R-HRP
Descrizione: Prickle1 is an 831 amino acid protein that contains one PET domain and three LIM zinc-binding domains and localizes to the cytoplasm, as well as to the nuclear membrane. Expressed at higher levels in placenta and at lower levels in liver, brain, kidney, lung and pancreas, Prickle1 is thought to function as a nuclear receptor that interacts with NRSF, a silencer protein that binds the DNA sequence element NRSE (neuron-restrictive silencer element). Defects in the gene encoding Prickle1 are associated with autosomal recessive progressive myoclonic epilepsy-1B, which is characterized by quick jerks of the arms, shoulders or legs. The gene encoding Prickle1 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9332R-A350

Anti-NHLRC2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Codice catalogo: (BOSSBS-9332R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-9332R-A350
Codice articolo locale: BOSSBS-9332R-A350
Descrizione: NHLRC2 (NHL repeat containing 2) is a 726 amino acid protein that contains six NHL repeats and one thioredoxin domain. Existing as two alternatively spliced isoforms, NHLRC2 is encoded by a gene that maps to human chromosome 10q25.3. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
UOM: 1 * 100 µl
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