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Codice catalogo: (BOSSBS-12859R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-12859R-CY3
Codice articolo locale: BOSSBS-12859R-CY3
Descrizione: Crystallins are the major proteins of the vertebrate eye lens, where they maintain the transparency and refractive index of the lens. Crystallins are divided into a, b, and g families, and the b- and g-crystallins also comprise a superfamily. Crystallins usually contain seven distinctive protein regions, including four homologous motifs, a connecting peptide, and N- and C-terminal extensions. b-crystallins constitute the major lens structural proteins. They associate into dimers, tetramers, and higher order aggregates. The b-crystallin subfamily is composed of several gene products, including bA1-, bA2-, bA3-, bA4-, bB1-, bB2- and bB3-crystallin. The bA1- and bA3-crystallin proteins are encoded by a single mRNA. They differ by only 17 amino acids, and bA1-crystallin is generated by use of an alternate translation initiation site. The genes for bA4-, bB1-, bB2- and bB3-crystallin are clustered on human chromosome 22q11, while the genes for bA3/A1- and bA2-crystallin map to human chromosomes 17q11 and 2q34, respectively.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-12859R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-12859R-A647
Codice articolo locale: BOSSBS-12859R-A647
Descrizione: Crystallins are the major proteins of the vertebrate eye lens, where they maintain the transparency and refractive index of the lens. Crystallins are divided into a, b, and g families, and the b- and g-crystallins also comprise a superfamily. Crystallins usually contain seven distinctive protein regions, including four homologous motifs, a connecting peptide, and N- and C-terminal extensions. b-crystallins constitute the major lens structural proteins. They associate into dimers, tetramers, and higher order aggregates. The b-crystallin subfamily is composed of several gene products, including bA1-, bA2-, bA3-, bA4-, bB1-, bB2- and bB3-crystallin. The bA1- and bA3-crystallin proteins are encoded by a single mRNA. They differ by only 17 amino acids, and bA1-crystallin is generated by use of an alternate translation initiation site. The genes for bA4-, bB1-, bB2- and bB3-crystallin are clustered on human chromosome 22q11, while the genes for bA3/A1- and bA2-crystallin map to human chromosomes 17q11 and 2q34, respectively.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-12859R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-12859R-A750
Codice articolo locale: BOSSBS-12859R-A750
Descrizione: Crystallins are the major proteins of the vertebrate eye lens, where they maintain the transparency and refractive index of the lens. Crystallins are divided into a, b, and g families, and the b- and g-crystallins also comprise a superfamily. Crystallins usually contain seven distinctive protein regions, including four homologous motifs, a connecting peptide, and N- and C-terminal extensions. b-crystallins constitute the major lens structural proteins. They associate into dimers, tetramers, and higher order aggregates. The b-crystallin subfamily is composed of several gene products, including bA1-, bA2-, bA3-, bA4-, bB1-, bB2- and bB3-crystallin. The bA1- and bA3-crystallin proteins are encoded by a single mRNA. They differ by only 17 amino acids, and bA1-crystallin is generated by use of an alternate translation initiation site. The genes for bA4-, bB1-, bB2- and bB3-crystallin are clustered on human chromosome 22q11, while the genes for bA3/A1- and bA2-crystallin map to human chromosomes 17q11 and 2q34, respectively.
UOM: 1 * 100 µl


Fornitore: Cayman Chemical
Descrizione: Okadaic acid

Codice catalogo: (BOSSBS-1967R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-1967R-HRP
Codice articolo locale: BOSSBS-1967R-HRP
Descrizione: Kallikrein 9, also known as Kallikrein-Like 3 (KLK-L3), is a chymotrypsin-like serine proteinase. Kallikrein 9 was discovered as the locus for kallikreins on chromosome 19 was more fully mapped and found by similarity to the other tissue kallikreins. Kallikrein 9 has been found in the ovary, thymus, testis, prostate, skin, breast and neuronal tissues and is made by many cell lines in culture. Kallikrein 9 levels in breast cancer and uterine cancer patients have been reported to drop as the disease progresses, thus hK9 might be considered a favorable prognostic marker. Different splice variants of hK9 have been reported, although it is not yet known if they produce functional proteins. The full length Kallikrein 9 encodes for a 250 amino acid protein, with a predicted mass of 27.5 kDa and a pI of 7.53. The 234 amino acid form predicts a protein of 26 kDa with a pI of 9.76 and this quite basic pI might give the shorter form a very different function or localization. The shorter sequence also diverges before the catalytic serine residue, making it unlikely to be proteolytically active. Pre-pro-kallikrein 9 has the 17 amino acid signal sequence is removed before secretion, and the Pro-kallikrein 9 is activated to Kallikrein 9 by removal of the 5 amino acid propeptide domain.
UOM: 1 * 100 µl


Fornitore: TCI
Descrizione: 1-Boc-1H-pyrazole-4-boronic acid pinacol ester ≥98.0% (by titrimetric analysis)

Codice catalogo: (PRSI7337P)
Fornitore: ProSci Inc.
Codice articolo fornitore: 7337P
Codice articolo locale: PRSI7337P
Descrizione: 17 amino acids near the center of human ULK2.
UOM: 1 * 50 µG


Codice catalogo: (PRSI7395P)
Fornitore: ProSci Inc.
Codice articolo fornitore: 7395P
Codice articolo locale: PRSI7395P
Descrizione: 17 amino acids near the center of human NCBP1.
UOM: 1 * 50 µG


Codice catalogo: (BOSSBS-10361R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-10361R-FITC
Codice articolo locale: BOSSBS-10361R-FITC
Descrizione: Fibrinogen is the main protein of blood coagulation system. It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N terminal parts of alpha and beta chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerization forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism and thromboses of arteries and veins, since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth and many other diseases. The normal fibrinogen concentration in plasma is about 3 mg/ml. The elevated level of fibrinogen in patient's blood is regarded as an independent risk factor for cardiovascular diseases. An increase in blood fibrinogen concentration was shown to be a strong predictor of coronary heart disease (Sonel A. et al, and Rapold H.J. et al). All these facts make fibrinogen an important parameter in the diagnosis of cardiovascular diseases.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-10361R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-10361R-A555
Codice articolo locale: BOSSBS-10361R-A555
Descrizione: Fibrinogen is the main protein of blood coagulation system. It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N terminal parts of alpha and beta chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerization forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism and thromboses of arteries and veins, since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth and many other diseases. The normal fibrinogen concentration in plasma is about 3 mg/ml. The elevated level of fibrinogen in patient's blood is regarded as an independent risk factor for cardiovascular diseases. An increase in blood fibrinogen concentration was shown to be a strong predictor of coronary heart disease (Sonel A. et al, and Rapold H.J. et al). All these facts make fibrinogen an important parameter in the diagnosis of cardiovascular diseases.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11607R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-11607R-A488
Codice articolo locale: BOSSBS-11607R-A488
Descrizione: The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. LRRC54 (leucine-rich repeat-containing protein 54), also known as tsukushin, TSKU or E2-induced gene 4 protein (E2IG4), is a 353 amino acid secreted protein that likely localizes to the cell membrane and extracellular compartments. Involved in extracellular secretion and intracellular transport, LRRC54 can be induced by 17-beta-estradiol. Containing nine LRR repeat and a cleavable signal peptide, the gene encoding LRRC54 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
UOM: 1 * 100 µl


Codice catalogo: (PRSI7225P)
Fornitore: ProSci Inc.
Codice articolo fornitore: 7225P
Codice articolo locale: PRSI7225P
Descrizione: 17 amino acids near the center of human NELF.
UOM: 1 * 50 µG


Codice catalogo: (PRSI7255P)
Fornitore: ProSci Inc.
Codice articolo fornitore: 7255P
Codice articolo locale: PRSI7255P
Descrizione: 17 amino acid peptide near the center of human FOXA1.
UOM: 1 * 50 µG


Codice catalogo: (PRSI7281P)
Fornitore: ProSci Inc.
Codice articolo fornitore: 7281P
Codice articolo locale: PRSI7281P
Descrizione: 17 amino acids near the carboxy terminus of human MTERFD1.
UOM: 1 * 50 µG


Codice catalogo: (PRSI7133P)
Fornitore: ProSci Inc.
Codice articolo fornitore: 7133P
Codice articolo locale: PRSI7133P
Descrizione: 17 amino acids near the carboxy terminus of human CHCHD6.
UOM: 1 * 50 µG


Codice catalogo: (PRSI7229P)
Fornitore: ProSci Inc.
Codice articolo fornitore: 7229P
Codice articolo locale: PRSI7229P
Descrizione: 17 amino acids near the carboxy terminus of human GRIP1.
UOM: 1 * 50 µG


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