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Image Unavailable-EHERC15977600

Acido Pimelico

Codice catalogo: (EHERC15977600)
Fornitore: EHRENSTORFER
Codice articolo fornitore: C15977600
Codice articolo locale: EHERC15977600
Descrizione: Acido Pimelico
UOM: 1 * 0,25 g
Image Unavailable-BOSSBS-12859R-A750

Anti-beta Crystallin A3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Codice catalogo: (BOSSBS-12859R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-12859R-A750
Codice articolo locale: BOSSBS-12859R-A750
Descrizione: Crystallins are the major proteins of the vertebrate eye lens, where they maintain the transparency and refractive index of the lens. Crystallins are divided into a, b, and g families, and the b- and g-crystallins also comprise a superfamily. Crystallins usually contain seven distinctive protein regions, including four homologous motifs, a connecting peptide, and N- and C-terminal extensions. b-crystallins constitute the major lens structural proteins. They associate into dimers, tetramers, and higher order aggregates. The b-crystallin subfamily is composed of several gene products, including bA1-, bA2-, bA3-, bA4-, bB1-, bB2- and bB3-crystallin. The bA1- and bA3-crystallin proteins are encoded by a single mRNA. They differ by only 17 amino acids, and bA1-crystallin is generated by use of an alternate translation initiation site. The genes for bA4-, bB1-, bB2- and bB3-crystallin are clustered on human chromosome 22q11, while the genes for bA3/A1- and bA2-crystallin map to human chromosomes 17q11 and 2q34, respectively.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12859R-A350

Anti-CRYBA1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Codice catalogo: (BOSSBS-12859R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-12859R-A350
Codice articolo locale: BOSSBS-12859R-A350
Descrizione: Crystallins are the major proteins of the vertebrate eye lens, where they maintain the transparency and refractive index of the lens. Crystallins are divided into a, b, and g families, and the b- and g-crystallins also comprise a superfamily. Crystallins usually contain seven distinctive protein regions, including four homologous motifs, a connecting peptide, and N- and C-terminal extensions. b-crystallins constitute the major lens structural proteins. They associate into dimers, tetramers, and higher order aggregates. The b-crystallin subfamily is composed of several gene products, including bA1-, bA2-, bA3-, bA4-, bB1-, bB2- and bB3-crystallin. The bA1- and bA3-crystallin proteins are encoded by a single mRNA. They differ by only 17 amino acids, and bA1-crystallin is generated by use of an alternate translation initiation site. The genes for bA4-, bB1-, bB2- and bB3-crystallin are clustered on human chromosome 22q11, while the genes for bA3/A1- and bA2-crystallin map to human chromosomes 17q11 and 2q34, respectively.
UOM: 1 * 100 µl
Image Unavailable-PRSI7225P

Human NELF peptide

Codice catalogo: (PRSI7225P)
Fornitore: ProSci Inc.
Codice articolo fornitore: 7225P
Codice articolo locale: PRSI7225P
Descrizione: 17 amino acids near the center of human NELF.
UOM: 1 * 50 µG
Image Unavailable-BOSSBS-1967R-A555

Anti-KLK9 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Codice catalogo: (BOSSBS-1967R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-1967R-A555
Codice articolo locale: BOSSBS-1967R-A555
Descrizione: Kallikrein 9, also known as Kallikrein-Like 3 (KLK-L3), is a chymotrypsin-like serine proteinase. Kallikrein 9 was discovered as the locus for kallikreins on chromosome 19 was more fully mapped and found by similarity to the other tissue kallikreins. Kallikrein 9 has been found in the ovary, thymus, testis, prostate, skin, breast and neuronal tissues and is made by many cell lines in culture. Kallikrein 9 levels in breast cancer and uterine cancer patients have been reported to drop as the disease progresses, thus hK9 might be considered a favorable prognostic marker. Different splice variants of hK9 have been reported, although it is not yet known if they produce functional proteins. The full length Kallikrein 9 encodes for a 250 amino acid protein, with a predicted mass of 27.5 kDa and a pI of 7.53. The 234 amino acid form predicts a protein of 26 kDa with a pI of 9.76 and this quite basic pI might give the shorter form a very different function or localization. The shorter sequence also diverges before the catalytic serine residue, making it unlikely to be proteolytically active. Pre-pro-kallikrein 9 has the 17 amino acid signal sequence is removed before secretion, and the Pro-kallikrein 9 is activated to Kallikrein 9 by removal of the 5 amino acid propeptide domain.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13521R-HRP

Anti-GPR17 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Codice catalogo: (BOSSBS-13521R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-13521R-HRP
Codice articolo locale: BOSSBS-13521R-HRP
Descrizione: G protein-coupled receptor 17, GPR17, also known as uracil nucleotide/cysteinyl leukotriene receptor or P2Y-like receptor (P2YL), is a 367 amino acid member of the G-protein coupled receptor 1 family of proteins. While GPR17 is expressed in kidney, heart and umbilical vein endothelial cells, it is expressed in the highest levels in the brain. Upon brain injury, the extracellular concentrations of nucleotides and cysteinyl leukotrienes (CysLTs), two families of endogenous signaling molecules, increase significantly at the site of damage. In some neurons, GPR17, a membrane receptor for uracil nucleotide and CysLTs, is upregulated as well, infiltrating the lesioned area. GPR17 is thought to play a role in mediating neuronal death, remodeling brain circuitries by microglia and initiating remyelination in damaged neurons. Two named isoforms of GPR17 exist as a result of alternative splicing events.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11296R-CY3

Anti-HSD17B4 Rabbit Polyclonal Antibody (Cy3®)

Codice catalogo: (BOSSBS-11296R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-11296R-CY3
Codice articolo locale: BOSSBS-11296R-CY3
Descrizione: 17Beta-HSD4 (17Beta-hydroxysteroid dehydrogenase type 4) is also known as peroxisomal multifunctional enzyme/protein 2 (MFE-2/MFP-2), D-bifunctional enzyme or 17-Beta Estradiol dehydrogenase type IV. It belongs to the 17Beta-HSD family of proteins that regulate the availability of steroids within various tissues throughout the body. 17Beta-HSD4 inactivates Estradiol through its oxidative activity but it is primarily involved in peroxisomal fatty acid and cholesterol Beta-oxidation. It has a multi-domain structure: the dehydrogenase domain is fused to a hydratase and a lipid transfer domain. 17Beta-HSD4 is a target protein of chromeceptin and it is essential for the downstream activation of Stat6. 17Beta-HSD4-deficient patients exhibit Zellweger-like syndrome and die within the first year of life. They display neuronal migration defects, facial dysmorphisms, severe hypotonia and convulsions in the neonatal period.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10361R-CY5

Anti-Bovine Fibrinogen Rabbit Polyclonal Antibody (Cy5®)

Codice catalogo: (BOSSBS-10361R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-10361R-CY5
Codice articolo locale: BOSSBS-10361R-CY5
Descrizione: Fibrinogen is the main protein of blood coagulation system. It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N terminal parts of alpha and beta chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerization forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism and thromboses of arteries and veins, since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth and many other diseases. The normal fibrinogen concentration in plasma is about 3 mg/ml. The elevated level of fibrinogen in patient's blood is regarded as an independent risk factor for cardiovascular diseases. An increase in blood fibrinogen concentration was shown to be a strong predictor of coronary heart disease (Sonel A. et al, and Rapold H.J. et al). All these facts make fibrinogen an important parameter in the diagnosis of cardiovascular diseases.
UOM: 1 * 100 µl
Product Image-PRSI7229P

Human GRIP1 peptide

Codice catalogo: (PRSI7229P)
Fornitore: ProSci Inc.
Codice articolo fornitore: 7229P
Codice articolo locale: PRSI7229P
Descrizione: 17 amino acids near the carboxy terminus of human GRIP1.
UOM: 1 * 50 µG
Image Unavailable-PRSI7133P

Human CHCHD6 peptide

Codice catalogo: (PRSI7133P)
Fornitore: ProSci Inc.
Codice articolo fornitore: 7133P
Codice articolo locale: PRSI7133P
Descrizione: 17 amino acids near the carboxy terminus of human CHCHD6.
UOM: 1 * 50 µG
Image Unavailable-PRSI7281P

Human MTERFD1 peptide

Codice catalogo: (PRSI7281P)
Fornitore: ProSci Inc.
Codice articolo fornitore: 7281P
Codice articolo locale: PRSI7281P
Descrizione: 17 amino acids near the carboxy terminus of human MTERFD1.
UOM: 1 * 50 µG
Image Unavailable-BOSSBS-11607R-A750

Anti-TSK/Tsukushin/LRRC54 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Codice catalogo: (BOSSBS-11607R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-11607R-A750
Codice articolo locale: BOSSBS-11607R-A750
Descrizione: The leucine-rich (LRR) repeat is a 20 to 30 amino acid motif that forms a hydrophobic / horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. LRRC54 (leucine-rich repeat-containing protein 54), also known as tsukushin, TSKU or E2-induced gene 4 protein (E2IG4), is a 353 amino acid secreted protein that likely localizes to the cell membrane and extracellular compartments. Involved in extracellular secretion and intracellular transport, LRRC54 can be induced by 17-beta-estradiol. Containing nine LRR repeat and a cleavable signal peptide, the gene encoding LRRC54 maps to human chromosome 11, which houses over 1400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12704R-CY7

Anti-SP6 Rabbit Polyclonal Antibody (Cy7®)

Codice catalogo: (BOSSBS-12704R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-12704R-CY7
Codice articolo locale: BOSSBS-12704R-CY7
Descrizione: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. Sp6, also known as EPFN, EPIPROFIN or KLF14, is a 376 amino acid protein that localizes to the nucleus and contains three C2H2-type zinc fingers. Expressed ubiquitously with higher expression in developing teeth, hair follicles and limb buds, Sp6 functions to bind GC-rich sequences and related GT and CACCC boxes, thereby promoting cellular proliferation. Human Sp6 shares 96% sequence homology with its mouse counterpart, suggesting a conserved role between species. The gene encoding Sp6 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12704R-A350

Anti-SP6 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Codice catalogo: (BOSSBS-12704R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-12704R-A350
Codice articolo locale: BOSSBS-12704R-A350
Descrizione: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. Sp6, also known as EPFN, EPIPROFIN or KLF14, is a 376 amino acid protein that localizes to the nucleus and contains three C2H2-type zinc fingers. Expressed ubiquitously with higher expression in developing teeth, hair follicles and limb buds, Sp6 functions to bind GC-rich sequences and related GT and CACCC boxes, thereby promoting cellular proliferation. Human Sp6 shares 96% sequence homology with its mouse counterpart, suggesting a conserved role between species. The gene encoding Sp6 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13574R-A750

Anti-ZBTB4/ZNF903 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Codice catalogo: (BOSSBS-13574R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-13574R-A750
Codice articolo locale: BOSSBS-13574R-A750
Descrizione: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZBTB4 (zinc finger and BTB domain containing 4), also known as KAISO-L1 (KAISO-like zinc finger protein 1), is a 1,013 amino acid nuclear protein that is involved in transcriptional regulation. ZBTB4 contains one BTB (POZ) domain, six C2H2-type zinc fingers and is phosphorylated and downregulated by HIPK2. The gene encoding ZBTB4 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13574R-CY5

Anti-ZBTB4 Rabbit Polyclonal Antibody (Cy5®)

Codice catalogo: (BOSSBS-13574R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-13574R-CY5
Codice articolo locale: BOSSBS-13574R-CY5
Descrizione: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZBTB4 (zinc finger and BTB domain containing 4), also known as KAISO-L1 (KAISO-like zinc finger protein 1), is a 1,013 amino acid nuclear protein that is involved in transcriptional regulation. ZBTB4 contains one BTB (POZ) domain, six C2H2-type zinc fingers and is phosphorylated and downregulated by HIPK2. The gene encoding ZBTB4 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.
UOM: 1 * 100 µl
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La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
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