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Image Unavailable-BOSSBS-9419R

Anti-TSPAN10 Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-9419R)
Fornitore: Bioss
Codice articolo fornitore: BS-9419R
Codice articolo locale: BOSSBS-9419R
Descrizione: The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. Oculospanin, also known as tetraspanin 10 (TSPAN10) or OCSP, is a 355 amino acid multi-pass membrane protein belonging to the tetraspanin (TM4SF) family. Oculospanin is expressed in certain regions of the eye such as retinal pigment epithelium, ciliary body and iris, but is not found in the lens. The gene encoding Oculospanin maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, and is liked to predisposition of cancers of the ovary, colon, prostate gland and fallopian tubes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11904R

Anti-NOTUM Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-11904R)
Fornitore: Bioss
Codice articolo fornitore: BS-11904R
Codice articolo locale: BOSSBS-11904R
Descrizione: Notum is a 496 amino acid secreted protein that belongs to the pectinacetylesterase family and may deacetylate GlcNAc residues on cell surface glycans. The gene that encodes Notum consists of approximately 9,334 bases and maps to human chromosome 17q25.3. Encoding more than 1,200 genes, chromosome 17 comprises over 2.5% of the human genome. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of ovary, colon, prostate gland and fallopian tubes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9203R-FITC

Anti-CD300C Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-9203R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-9203R-FITC
Codice articolo locale: BOSSBS-9203R-FITC
Descrizione: CD300C , also known as CLM-6 (CMRF35-like molecule 6), is a 224 amino acid single-pass type I membrane protein that is present on the surface of neutrophils, monocytes and a select proportion of peripheral blood B and T lymphocytes. CD300C contains two potential N-gylcosylation sites, a potential O-glycosylated hinge-like region and an Ig-like V-type (immunoglobulin-like) domain that is very similar to the Fc receptor for polymeric IgA and IgM. The gene encoding CD300C is localized to a region on human chromosome 17 that harbors a susceptilibty locus for psoriasis, dermatitis and rheumatoid arthritis, suggesting a possible involvement of CD300C with these conditions.
UOM: 1 * 100 µl
Image Unavailable-APOSOR9998-100MG

Methyl (2,3-dihydro-3-oxo-4H-1,4-benzothiazin-4-yl)acetate

Codice catalogo: (APOSOR9998-100MG)
Fornitore: Apollo Scientific
Codice articolo fornitore: OR9998-100MG
Codice articolo locale: APOSOR9998-100MG
Descrizione: Methyl (2,3-dihydro-3-oxo-4H-1,4-benzothiazin-4-yl)acetate
UOM: 1 * 100 mg
Image Unavailable-BOSSBS-9289R-A488

Anti-PACRG Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Codice catalogo: (BOSSBS-9289R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-9289R-A488
Codice articolo locale: BOSSBS-9289R-A488
Descrizione: The deduced 257 amino acid protein PACRG (Parkin co-regulated gene) shows potential links to the ubiquitin/proteasome system. PACRG and Parkin are attached in a head-to-head arrangement on opposite DNA strands and share a common 5' flanking promoter region. The PACRG gene maps to chromosome 6q26; Northern blot analysis detects PACRG expression in all tissues examined except placenta. Using a positional cloning strategy in 197 Vietnamese leprosy simplex families (i.e. families with two unaffected parents and one affected child), significant connections between leprosy and 17 markers in the 5' regulatory region that PARK2 and PACRG share were observed. Possession of two or more of the 17 risk alleles is highly predictive of leprosy.PACRG is a gene located very close to parkin, in reverse orientation on the chromosome. It is thought to be co-transcribed with parkin by a bi-directional promoter between the two genes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11904R-FITC

Anti-NOTUM Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-11904R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-11904R-FITC
Codice articolo locale: BOSSBS-11904R-FITC
Descrizione: Notum is a 496 amino acid secreted protein that belongs to the pectinacetylesterase family and may deacetylate GlcNAc residues on cell surface glycans. The gene that encodes Notum consists of approximately 9,334 bases and maps to human chromosome 17q25.3. Encoding more than 1,200 genes, chromosome 17 comprises over 2.5% of the human genome. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of ovary, colon, prostate gland and fallopian tubes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8418R-A647

Anti-HEXDC Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-8418R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-8418R-A647
Codice articolo locale: BOSSBS-8418R-A647
Descrizione: HEXDC, also known as hexosaminidase D, beta-hexosaminidase D, N-acetyl-beta-galactosaminidase, hexosaminidase domain-containing protein or beta-N-acetylhexosaminidase, is a 486 amino acid cytoplasmic and nuclear protein that has hexosaminidase activity and belongs to the glycosyl hydrolase 20 family. Existing as two alternatively spliced isoforms, HEXDC catalyzes the hydrolysis of non-reducing N-acetyl-D-hexosamine residues near the termini of N-acetyl-beta-D-hexosaminides. The gene encoding HEXDC maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Defects in p53 is associated with malignant cell growth and Li-Fraumeni syndrome. BRCA1 is directly involved in DNA repair and is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8418R-A555

Anti-HEXDC Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Codice catalogo: (BOSSBS-8418R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-8418R-A555
Codice articolo locale: BOSSBS-8418R-A555
Descrizione: HEXDC, also known as hexosaminidase D, beta-hexosaminidase D, N-acetyl-beta-galactosaminidase, hexosaminidase domain-containing protein or beta-N-acetylhexosaminidase, is a 486 amino acid cytoplasmic and nuclear protein that has hexosaminidase activity and belongs to the glycosyl hydrolase 20 family. Existing as two alternatively spliced isoforms, HEXDC catalyzes the hydrolysis of non-reducing N-acetyl-D-hexosamine residues near the termini of N-acetyl-beta-D-hexosaminides. The gene encoding HEXDC maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Defects in p53 is associated with malignant cell growth and Li-Fraumeni syndrome. BRCA1 is directly involved in DNA repair and is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8418R-A350

Anti-HEXDC Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Codice catalogo: (BOSSBS-8418R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-8418R-A350
Codice articolo locale: BOSSBS-8418R-A350
Descrizione: HEXDC, also known as hexosaminidase D, beta-hexosaminidase D, N-acetyl-beta-galactosaminidase, hexosaminidase domain-containing protein or beta-N-acetylhexosaminidase, is a 486 amino acid cytoplasmic and nuclear protein that has hexosaminidase activity and belongs to the glycosyl hydrolase 20 family. Existing as two alternatively spliced isoforms, HEXDC catalyzes the hydrolysis of non-reducing N-acetyl-D-hexosamine residues near the termini of N-acetyl-beta-D-hexosaminides. The gene encoding HEXDC maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Defects in p53 is associated with malignant cell growth and Li-Fraumeni syndrome. BRCA1 is directly involved in DNA repair and is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8418R-A488

Anti-HEXDC Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Codice catalogo: (BOSSBS-8418R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-8418R-A488
Codice articolo locale: BOSSBS-8418R-A488
Descrizione: HEXDC, also known as hexosaminidase D, beta-hexosaminidase D, N-acetyl-beta-galactosaminidase, hexosaminidase domain-containing protein or beta-N-acetylhexosaminidase, is a 486 amino acid cytoplasmic and nuclear protein that has hexosaminidase activity and belongs to the glycosyl hydrolase 20 family. Existing as two alternatively spliced isoforms, HEXDC catalyzes the hydrolysis of non-reducing N-acetyl-D-hexosamine residues near the termini of N-acetyl-beta-D-hexosaminides. The gene encoding HEXDC maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Defects in p53 is associated with malignant cell growth and Li-Fraumeni syndrome. BRCA1 is directly involved in DNA repair and is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8361R

Anti-LRRC59 Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-8361R)
Fornitore: Bioss
Codice articolo fornitore: BS-8361R
Codice articolo locale: BOSSBS-8361R
Descrizione: LRRC59 (leucine rich repeat containing 59), also known as PRO1855, is a 307 amino acid protein that contains leucine-rich repeats and may play a role in protein binding events throughout the cell. The gene encoding LRRC59 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9638R

Anti-DERP6 Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-9638R)
Fornitore: Bioss
Codice articolo fornitore: BS-9638R
Codice articolo locale: BOSSBS-9638R
Descrizione: DERP6, is a 316 amino acid protein that localizes to the cytoplasm and exists as multiple alternatively spliced isoforms. Expressed ubiquitously with highest expression in liver, heart, testis, brain and skeletal muscle, DERP6 is thought to be involved in p53-mediated transcriptional regulation. The gene encoding DERP6 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13614R

Anti-MYCBPAP Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-13614R)
Fornitore: Bioss
Codice articolo fornitore: BS-13614R
Codice articolo locale: BOSSBS-13614R
Descrizione: AMAP-1 (AMY-1-binding protein 1), also known as AMAM-1 or MYCBPAP (MYCBP associated protein), is a 947 amino acid protein that is expressed specifically in testis and is involved in spermatogenesis and synaptic processes. AMAP-1 colocalizes with MYCBP (AMY-1) in cytoplasm and also localizes to membrane. The gene encoding AMAP-1 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9596R-CY5

Anti-SPAG17 Rabbit Polyclonal Antibody (Cy5®)

Codice catalogo: (BOSSBS-9596R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-9596R-CY5
Codice articolo locale: BOSSBS-9596R-CY5
Descrizione: SPAG17 (sperm associated antigen 17), also known as PF6, is a 2,223 amino acid cytoplamic protein that colocalizes with SPAG6 to microtubles. Highly expressed in testis and in organs that contain cilia-bearing cells including brain, oviduct, lung, and uterus, SPAG17 may be important for the structural integrity of the central apparatus of the sperm axoneme. SPAG17 contains two LRR (leucine-rich) repeats and may also participate in flagellar motility and male fertility.
UOM: 1 * 100 µl
Image Unavailable-TCIAA2456-5G

Alendronate sodium trihydrate ≥97.0% (by titrimetric analysis)

Fornitore: TCI
Descrizione: Alendronate sodium trihydrate ≥97.0% (by titrimetric analysis)

Image Unavailable-BOSSBS-9745R-A750

Anti-ANKRD13B Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Codice catalogo: (BOSSBS-9745R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-9745R-A750
Codice articolo locale: BOSSBS-9745R-A750
Descrizione: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes can lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD13B (ankyrin repeat domain 13B) is a 626 amino acid protein that contains two ANK repeats and three ubiquitin-interacting motif (UIM) repeats. Conserved in dog, cow, mouse and rat, ANKRD13B exists as two alternatively spliced isoforms. The gene that encodes ANKRD13B maps to human chromosome 17, which makes up over 2.5% of the human genome, with about 81 million bases encoding over 1200 genes. Two key tumour suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. BRCA1 is recognised as a genetic determinant of early onset breast cancer. Chromosome 17 is also linked to neurofibromatosis, dysregulated Schwann cell growth, Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease.
UOM: 1 * 100 µl
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