Hai cercato: 1-Methyl-N-carbobenzoxy-L-glutamate

Codice catalogo: (BOSSBS-13263R-CY5)

Fornitore: Bioss

Codice articolo fornitore: BS-13263R-CY5

Codice articolo locale: BOSSBS-13263R-CY5

Descrizione: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma aminobutyric acid from L glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin dependent diabetes. This gene may also play a role in the stiff man syndrome.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-13264R-CY5)

Fornitore: Bioss

Codice articolo fornitore: BS-13264R-CY5

Codice articolo locale: BOSSBS-13264R-CY5

Descrizione: There are two forms of glutamic acid decarboxylases (GADs) that exist in brain: GAD-65 (also known as GAD2) and GAD-67 (also known as GAD1, GAD or SCP). GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 transiently activates to assist in GABA production. As a member of the group II decarboxylase family, GADL1 (Glutamate decarboxylase-like protein 1) is a 521 amino acid protein that utilizes pyridoxal phosphate as a cofactor for its carboxylase activity. There are two isoforms of GADL1 that exist as a result of alternative splicing events.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-10157R)

Fornitore: Bioss

Codice articolo fornitore: BS-10157R

Codice articolo locale: BOSSBS-10157R

Descrizione: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-1894R-CY5)

Fornitore: Bioss

Codice articolo fornitore: BS-1894R-CY5

Codice articolo locale: BOSSBS-1894R-CY5

Descrizione: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-4142R)

Fornitore: Bioss

Codice articolo fornitore: BS-4142R

Codice articolo locale: BOSSBS-4142R

Descrizione: May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.

UOM: 1 * 100 µl

Promo

Codice catalogo: (1294987.)

Fornitore: USP

Codice articolo fornitore: 1294987

Codice articolo locale: USPH1294987

Descrizione: USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.

UOM: 1 * 100 mg

Promo

Codice catalogo: (BOSSBS-3507R-HRP)

Fornitore: Bioss

Codice articolo fornitore: BS-3507R-HRP

Codice articolo locale: BOSSBS-3507R-HRP

Descrizione: NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-8403R)

Fornitore: Bioss

Codice articolo fornitore: BS-8403R

Codice articolo locale: BOSSBS-8403R

Descrizione: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Synaptic and extrasynaptic NMDA receptors have been shown to have opposite effects on neuronal survival, CREB function and gene regulation. Gcom1 (GRINL1A complex locus protein 1), also known as GUP (GRINL1A upstream protein) and Gcom (GRINL1A combined protein), is a 466 amino acid protein that is a component of the GRINL1A complex transcription unit, which is thought to be involved in the modulation of glutamatergic neurotransmission through interaction with the NR1 subunit of the NMDA receptor. Gcom1 is expressed in small intestine, lung, liver, heart, skeletal muscle, testis and prostate and also colocalizes with NR1 in cortical and hippocampal neurons. There are eleven isoforms of Gcom1 that are produced as a result of alternative splicing events.

UOM: 1 * 100 µl

Promo

Codice catalogo: (USBI036296-BIOTIN)

Fornitore: US Biological

Codice articolo fornitore: 036296-BIOTIN

Codice articolo locale: USBI036296-BIOTIN

Descrizione: Anti-GRIK5 Rabbit Polyclonal Antibody (Biotin)

UOM: 1 * 200 µl

Promo

Codice catalogo: (BOSSBS-6883R-HRP)

Fornitore: Bioss

Codice articolo fornitore: BS-6883R-HRP

Codice articolo locale: BOSSBS-6883R-HRP

Descrizione: Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-0400R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-0400R-FITC

Codice articolo locale: BOSSBS-0400R-FITC

Descrizione: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-0400R-A555)

Fornitore: Bioss

Codice articolo fornitore: BS-0400R-A555

Codice articolo locale: BOSSBS-0400R-A555

Descrizione: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-0400R)

Fornitore: Bioss

Codice articolo fornitore: BS-0400R

Codice articolo locale: BOSSBS-0400R

Descrizione: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalysing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-0400R-CY5)

Fornitore: Bioss

Codice articolo fornitore: BS-0400R-CY5

Codice articolo locale: BOSSBS-0400R-CY5

Descrizione: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-4142R-HRP)

Fornitore: Bioss

Codice articolo fornitore: BS-4142R-HRP

Codice articolo locale: BOSSBS-4142R-HRP

Descrizione: May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-4142R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-4142R-A680

Codice articolo locale: BOSSBS-4142R-A680

Descrizione: May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.

UOM: 1 * 100 µl

Promo