Hai cercato: 1-Methyl-N-carbobenzoxy-L-glutamate

Codice catalogo: (BOSSBS-13046R-A488)

Fornitore: Bioss

Codice articolo fornitore: BS-13046R-A488

Codice articolo locale: BOSSBS-13046R-A488

Descrizione: Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate transporter that is expressed predominantly in the cerebellum. The transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar transport activities. EAAT5 is a glutamate transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-13046R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-13046R-A350

Codice articolo locale: BOSSBS-13046R-A350

Descrizione: Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate transporter that is expressed predominantly in the cerebellum. The transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar transport activities. EAAT5 is a glutamate transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-13046R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-13046R-A680

Codice articolo locale: BOSSBS-13046R-A680

Descrizione: Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate transporter that is expressed predominantly in the cerebellum. The transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar transport activities. EAAT5 is a glutamate transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-7124R)

Fornitore: Bioss

Codice articolo fornitore: BS-7124R

Codice articolo locale: BOSSBS-7124R

Descrizione: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for fast excitatory neurotransmission by glutamate, whereas the NMDA receptors exhibit slow kinetics of Ca2+ ions and a high permeability for Ca2+ ions.

UOM: 1 * 100 µl

Promo

Fornitore: Thermo Fisher Scientific

Descrizione: Boc-D-Glu-OtBu 95%

Certificati

Codice catalogo: (H63172.06)

Fornitore: Thermo Fisher Scientific

Codice articolo fornitore: H63172.06

Codice articolo locale: ALFAH63172.06

Descrizione: Boc-D-Glu(OtBu)-OH 98%

UOM: 1 * 5 g

Certificati Promo

Fornitore: Abcam

Descrizione: Anti-Metabotropic Glutamate Receptor 3/MGLUR3 Rabbit Monoclonal Antibody [clone: EPR24635-17]

Fornitore: Thermo Fisher Scientific

Descrizione: H-Glu(OtBu)-OtBu·HCl 98%

Certificati

Codice catalogo: (ABCAAB283572-100)

Fornitore: Abcam

Codice articolo fornitore: AB283572-100

Codice articolo locale: ABCAAB283572-100

Descrizione: Anti-Metabotropic Glutamate Receptor 3/MGLUR3 Rabbit Monoclonal Antibody [clone: EPR24635-17]

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-13046R-A555)

Fornitore: Bioss

Codice articolo fornitore: BS-13046R-A555

Codice articolo locale: BOSSBS-13046R-A555

Descrizione: Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate transporter that is expressed predominantly in the cerebellum. The transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar transport activities. EAAT5 is a glutamate transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-13046R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-13046R-CY3

Codice articolo locale: BOSSBS-13046R-CY3

Descrizione: Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate transporter that is expressed predominantly in the cerebellum. The transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar transport activities. EAAT5 is a glutamate transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-13046R-A750)

Fornitore: Bioss

Codice articolo fornitore: BS-13046R-A750

Codice articolo locale: BOSSBS-13046R-A750

Descrizione: Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate transporter that is expressed predominantly in the cerebellum. The transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar transport activities. EAAT5 is a glutamate transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.

UOM: 1 * 100 µl

Promo

Codice catalogo: (ABCAAB313151-100UL)

Fornitore: Abcam

Codice articolo fornitore: AB313151-100UL

Codice articolo locale: ABCAAB313151-100UL

Descrizione: Anti-Metabotropic Glutamate Receptor 5 Rabbit Monoclonal Antibody [clone: EPR2425Y] (Alexa Fluor® 555)

UOM: 1 * 100 µl

Promo

Codice catalogo: (ABCAAB312940-100UL)

Fornitore: Abcam

Codice articolo fornitore: AB312940-100UL

Codice articolo locale: ABCAAB312940-100UL

Descrizione: Anti-Metabotropic Glutamate Receptor 5 Rabbit Monoclonal Antibody [clone: EPR2425Y] (Alexa Fluor® 568)

UOM: 1 * 100 µl

Promo

Fornitore: TCI

Descrizione: N-(tert-Butoxycarbonyl)-L-pyroglutamic acid ≥98.0% (by HPLC, titration analysis)

Codice catalogo: (BOSSBS-12033R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-12033R-A680

Codice articolo locale: BOSSBS-12033R-A680

Descrizione: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localised with NMDA receptors in many synapses and consist of the structurally related subunits GluR-1 to -7, KA1 and KA2. KA1 (also designated EEA1) and KA2 (also designated EEA2) form heteromeric receptors with GluR subunits when coexpressed, forming ion channels with various properties. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate.

UOM: 1 * 100 µl

Promo