Stampa…

Hai cercato: 4,5-Dichloroisothiazole-3-carboxylic+acid


23 501  risultati sono stati trovati

Perfeziona la ricerca Seleziona per
SearchResultCount:"23501"

Sort Results

Visualizzazione a lista Nuova Visualizzazione

La tua valutazione

Image Unavailable-BOSSBS-6239R-CY7

Anti-SH3KBP1 Rabbit Polyclonal Antibody (Cy7®)

Codice catalogo: (BOSSBS-6239R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-6239R-CY7
Codice articolo locale: BOSSBS-6239R-CY7
Descrizione: SH3KBP1 belongs to the CIN85/CMS family of adaptor molecules, characterized by containing three N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The different members of the family orchestrate a network involved in dowregulation and degradation of recpetor tyrosine kinases. SH3KBP1 is involved in regulating diverse signal transduction pathways. Involved in the regulation of endocytosis and lysosomal degradation of ligand-induced receptor tyrosine kinases, including EGFR and MET/hepatocyte growth factor receptor, through a association with CBL and endophilins. In the case of EGF receptor turnover, its activation involves recruitment of SH3KBP1- endophilin complexes to mediate internalization. Once internalized, RTKs are delivered into the endosomal compartment where receptors get sorted for either recycling back to the cell surface or are targeted to lysosomes for degradation. Alternate splicing results in multiple transcript variants.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6239R-A680

Anti-SH3KBP1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-6239R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-6239R-A680
Codice articolo locale: BOSSBS-6239R-A680
Descrizione: SH3KBP1 belongs to the CIN85/CMS family of adaptor molecules, characterised by containing three N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The different members of the family orchestrate a network involved in dowregulation and degradation of recpetor tyrosine kinases. SH3KBP1 is involved in regulating diverse signal transduction pathways. Involved in the regulation of endocytosis and lysosomal degradation of ligand-induced receptor tyrosine kinases, including EGFR and MET/hepatocyte growth factor receptor, through a association with CBL and endophilins. In the case of EGF receptor turnover, its activation involves recruitment of SH3KBP1- endophilin complexes to mediate internalisation. Once internalised, RTKs are delivered into the endosomal compartment where receptors get sorted for either recycling back to the cell surface or are targeted to lysosomes for degradation. Alternate splicing results in multiple transcript variants.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6239R-HRP

Anti-SH3KBP1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Codice catalogo: (BOSSBS-6239R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-6239R-HRP
Codice articolo locale: BOSSBS-6239R-HRP
Descrizione: SH3KBP1 belongs to the CIN85/CMS family of adaptor molecules, characterized by containing three N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The different members of the family orchestrate a network involved in dowregulation and degradation of recpetor tyrosine kinases. SH3KBP1 is involved in regulating diverse signal transduction pathways. Involved in the regulation of endocytosis and lysosomal degradation of ligand-induced receptor tyrosine kinases, including EGFR and MET/hepatocyte growth factor receptor, through a association with CBL and endophilins. In the case of EGF receptor turnover, its activation involves recruitment of SH3KBP1- endophilin complexes to mediate internalization. Once internalized, RTKs are delivered into the endosomal compartment where receptors get sorted for either recycling back to the cell surface or are targeted to lysosomes for degradation. Alternate splicing results in multiple transcript variants.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6239R-CY5.5

Anti-SH3KBP1 Rabbit Polyclonal Antibody (Cy5.5®)

Codice catalogo: (BOSSBS-6239R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-6239R-CY5.5
Codice articolo locale: BOSSBS-6239R-CY5.5
Descrizione: SH3KBP1 belongs to the CIN85/CMS family of adaptor molecules, characterized by containing three N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The different members of the family orchestrate a network involved in dowregulation and degradation of recpetor tyrosine kinases. SH3KBP1 is involved in regulating diverse signal transduction pathways. Involved in the regulation of endocytosis and lysosomal degradation of ligand-induced receptor tyrosine kinases, including EGFR and MET/hepatocyte growth factor receptor, through a association with CBL and endophilins. In the case of EGF receptor turnover, its activation involves recruitment of SH3KBP1- endophilin complexes to mediate internalization. Once internalized, RTKs are delivered into the endosomal compartment where receptors get sorted for either recycling back to the cell surface or are targeted to lysosomes for degradation. Alternate splicing results in multiple transcript variants.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7752R-CY5.5

Anti-KLHL13 Rabbit Polyclonal Antibody (Cy5.5®)

Codice catalogo: (BOSSBS-7752R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-7752R-CY5.5
Codice articolo locale: BOSSBS-7752R-CY5.5
Descrizione: KLHL13 (kelch like 13), also known as BKLHD2 (BTB and kelch domain containing protein 2), is a 604 amino acid protein that contains six Kelch repeats and one BTB/POZ domain. Expressed predominantly in brain, KLHL13 is believed to play a role in protein ubiquitination and may function as a substrate specific adapter of an E3 ubiquitin protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, KLHL13 interacts with KLHL9 and CUL3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin mediated proteolysis. Via its BTB and C terminal Kelch (BACK) motif, KLHL13 is thought to play a role in spatially orientating substrates in the CUL3 ligase.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7752R-CY3

Anti-KLHL13 Rabbit Polyclonal Antibody (Cy3®)

Codice catalogo: (BOSSBS-7752R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-7752R-CY3
Codice articolo locale: BOSSBS-7752R-CY3
Descrizione: KLHL13 (kelch like 13), also known as BKLHD2 (BTB and kelch domain containing protein 2), is a 604 amino acid protein that contains six Kelch repeats and one BTB/POZ domain. Expressed predominantly in brain, KLHL13 is believed to play a role in protein ubiquitination and may function as a substrate specific adapter of an E3 ubiquitin protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, KLHL13 interacts with KLHL9 and CUL3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin mediated proteolysis. Via its BTB and C terminal Kelch (BACK) motif, KLHL13 is thought to play a role in spatially orientating substrates in the CUL3 ligase.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7752R-FITC

Anti-KLHL13 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-7752R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-7752R-FITC
Codice articolo locale: BOSSBS-7752R-FITC
Descrizione: KLHL13 (kelch like 13), also known as BKLHD2 (BTB and kelch domain containing protein 2), is a 604 amino acid protein that contains six Kelch repeats and one BTB/POZ domain. Expressed predominantly in brain, KLHL13 is believed to play a role in protein ubiquitination and may function as a substrate specific adapter of an E3 ubiquitin protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, KLHL13 interacts with KLHL9 and CUL3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin mediated proteolysis. Via its BTB and C terminal Kelch (BACK) motif, KLHL13 is thought to play a role in spatially orientating substrates in the CUL3 ligase.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8400R-A555

Anti-BTBD17 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Codice catalogo: (BOSSBS-8400R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-8400R-A555
Codice articolo locale: BOSSBS-8400R-A555
Descrizione: The BTB (broad-complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. BTBD17 (BTB/POZ domain-containing protein 17), also known as BTBD17A, galectin-3-binding protein-like or LGALS3BPL, is a 478 amino acid protein that contains one BTB (POZ) domain and a BACK (BTB/Kelch associated) domain. The gene encoding BTBD17 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8400R-CY5

Anti-BTBD17 Rabbit Polyclonal Antibody (Cy5®)

Codice catalogo: (BOSSBS-8400R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-8400R-CY5
Codice articolo locale: BOSSBS-8400R-CY5
Descrizione: The BTB (broad-complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. BTBD17 (BTB/POZ domain-containing protein 17), also known as BTBD17A, galectin-3-binding protein-like or LGALS3BPL, is a 478 amino acid protein that contains one BTB (POZ) domain and a BACK (BTB/Kelch associated) domain. The gene encoding BTBD17 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8400R-HRP

Anti-BTBD17 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Codice catalogo: (BOSSBS-8400R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-8400R-HRP
Codice articolo locale: BOSSBS-8400R-HRP
Descrizione: The BTB (broad-complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. BTBD17 (BTB/POZ domain-containing protein 17), also known as BTBD17A, galectin-3-binding protein-like or LGALS3BPL, is a 478 amino acid protein that contains one BTB (POZ) domain and a BACK (BTB/Kelch associated) domain. The gene encoding BTBD17 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12464R

Anti-COPA Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-12464R)
Fornitore: Bioss
Codice articolo fornitore: BS-12464R
Codice articolo locale: BOSSBS-12464R
Descrizione: COPA (alpha-coat protein) is processed to produce Xenin. Xenin stimulates exocrine pancreatic secretion to affect small and large intestinal motility, and inhibits pentagastrin-stimulated secretion of acid. In the gut, Xenin interacts with the neurotensin receptor. Membrane and vesicular trafficking in the early secretory pathway are mediated by non-Clathrin COP (coat protein) I-coated vesicles. COPI-coated vesicles mediate retrograde transport from the Golgi back to the ER and intra-Golgi transport. The cytosolic precursor of the COPI coat, the heptameric coatomer complex, is composed of two subcomplexes. The first consists of the COPB, COPG, COPD and COPZ subunits (also known as b-, g-, d- and z-COP, respectively), which are distantly homologous to AP Clathrin adaptor subunits. The second consists of the COPA, b'-COP and COPE subunits (also known as a-COP, COPP and e-COP, respectively).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12464R-A350

Anti-COPA Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Codice catalogo: (BOSSBS-12464R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-12464R-A350
Codice articolo locale: BOSSBS-12464R-A350
Descrizione: COPA (alpha-coat protein) is processed to produce Xenin. Xenin stimulates exocrine pancreatic secretion to affect small and large intestinal motility, and inhibits pentagastrin-stimulated secretion of acid. In the gut, Xenin interacts with the neurotensin receptor. Membrane and vesicular trafficking in the early secretory pathway are mediated by non-Clathrin COP (coat protein) I-coated vesicles. COPI-coated vesicles mediate retrograde transport from the Golgi back to the ER and intra-Golgi transport. The cytosolic precursor of the COPI coat, the heptameric coatomer complex, is composed of two subcomplexes. The first consists of the COPB, COPG, COPD and COPZ subunits (also known as b-, g-, d- and z-COP, respectively), which are distantly homologous to AP Clathrin adaptor subunits. The second consists of the COPA, b'-COP and COPE subunits (also known as a-COP, COPP and e-COP, respectively).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12464R-A555

Anti-COPA Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Codice catalogo: (BOSSBS-12464R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-12464R-A555
Codice articolo locale: BOSSBS-12464R-A555
Descrizione: COPA (alpha-coat protein) is processed to produce Xenin. Xenin stimulates exocrine pancreatic secretion to affect small and large intestinal motility, and inhibits pentagastrin-stimulated secretion of acid. In the gut, Xenin interacts with the neurotensin receptor. Membrane and vesicular trafficking in the early secretory pathway are mediated by non-Clathrin COP (coat protein) I-coated vesicles. COPI-coated vesicles mediate retrograde transport from the Golgi back to the ER and intra-Golgi transport. The cytosolic precursor of the COPI coat, the heptameric coatomer complex, is composed of two subcomplexes. The first consists of the COPB, COPG, COPD and COPZ subunits (also known as b-, g-, d- and z-COP, respectively), which are distantly homologous to AP Clathrin adaptor subunits. The second consists of the COPA, b'-COP and COPE subunits (also known as a-COP, COPP and e-COP, respectively).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12464R-A647

Anti-COPA Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-12464R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-12464R-A647
Codice articolo locale: BOSSBS-12464R-A647
Descrizione: COPA (alpha-coat protein) is processed to produce Xenin. Xenin stimulates exocrine pancreatic secretion to affect small and large intestinal motility, and inhibits pentagastrin-stimulated secretion of acid. In the gut, Xenin interacts with the neurotensin receptor. Membrane and vesicular trafficking in the early secretory pathway are mediated by non-Clathrin COP (coat protein) I-coated vesicles. COPI-coated vesicles mediate retrograde transport from the Golgi back to the ER and intra-Golgi transport. The cytosolic precursor of the COPI coat, the heptameric coatomer complex, is composed of two subcomplexes. The first consists of the COPB, COPG, COPD and COPZ subunits (also known as b-, g-, d- and z-COP, respectively), which are distantly homologous to AP Clathrin adaptor subunits. The second consists of the COPA, b'-COP and COPE subunits (also known as a-COP, COPP and e-COP, respectively).
UOM: 1 * 100 µl
Product Image-PRSI26-941

Anti-GTPBP4 Rabbit Polyclonal Antibody

Codice catalogo: (PRSI26-941)
Fornitore: ProSci Inc.
Codice articolo fornitore: 26-941
Codice articolo locale: PRSI26-941
Descrizione: GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.
UOM: 1 * 50 µG
Image Unavailable-BOSSBS-6239R-A555

Anti-SH3KBP1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Codice catalogo: (BOSSBS-6239R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-6239R-A555
Codice articolo locale: BOSSBS-6239R-A555
Descrizione: SH3KBP1 belongs to the CIN85/CMS family of adaptor molecules, characterized by containing three N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The different members of the family orchestrate a network involved in dowregulation and degradation of recpetor tyrosine kinases. SH3KBP1 is involved in regulating diverse signal transduction pathways. Involved in the regulation of endocytosis and lysosomal degradation of ligand-induced receptor tyrosine kinases, including EGFR and MET/hepatocyte growth factor receptor, through a association with CBL and endophilins. In the case of EGF receptor turnover, its activation involves recruitment of SH3KBP1- endophilin complexes to mediate internalization. Once internalized, RTKs are delivered into the endosomal compartment where receptors get sorted for either recycling back to the cell surface or are targeted to lysosomes for degradation. Alternate splicing results in multiple transcript variants.
UOM: 1 * 100 µl
Prezzo a richiesta
La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
Puoi ordinare questo prodotto. Se necessario, ti contatteremo per richiedere licenza, autorizzazione o dichiarazione d'uso per procedere con la fornitura.
Puoi ordinare questo prodotto. Se necessario, ti contatteremo per richiedere licenza, autorizzazione o dichiarazione d'uso per procedere con la fornitura.
Questo prodotto è stato bloccato dalla vostra organizzazione. Si prega di contattare il vostro responsabile acquisti per ulteriori informazioni.
Il prodotto originale non è più disponibile. L'articolo suggerito è disponibile
Il prodotto marcato con questo simbolo non è più disponibile o vendibile fino ad esaurimento scorte. Alternative possono essere disponibili utilizzando il numero di catalogo VWR. Per maggiori informazioni può contattare il nostro customer service al 023320311 o inviando una email all'indirizzo ebusiness.italy@avantorsciences.com
177 - 192 of 23 501
no targeter for Bottom