Hai cercato: (Z)-4-Hydroxytamoxifen

Fornitore: ENZO LIFE SCIENCES AG

Descrizione: Tamoxifen metabolite

New Product

Fornitore: Merck

Descrizione: Organic Standard, 4-Hydroxytamoxifen, (E) and (Z) isomers (50:50)

Codice catalogo: (94873-10MG)

Fornitore: Merck

Codice articolo fornitore: 94873-10MG

Codice articolo locale: SUPL94873-10MG

Descrizione: Organic Standard, 4-Hydroxytamoxifen, (E) and (Z) isomers (50:50)

UOM: 1 * 10 mg

Promo

Codice catalogo: (469501000.)

Fornitore: Thermo Scientific

Codice articolo fornitore: 469501000

Codice articolo locale: ACRO469501000

Descrizione: (Z)-4-Hydroxytamoxifen 99%

UOM: 1 * 100 mg

New Product Promo

Fornitore: MP Biomedicals

Descrizione: Protein kinase C inhibitor (IC50 = 50-200 µM depending on assay conditions in MCF-7 cells or IC50 = 100 µM in rat brain). The PKC inhibition is also dependent on the phosopholipid concentration. Also inhibits both calmodulin-dependent and calmodulin-independent Ca2+-, Mg2+-ATPase. Tamoxifen is a selective estrogen response modifier (SERM), anti-angiogenetic factor. It is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells.
Tamoxifen has been used to facilitate the recombination of ect2flox allele in mouse organs. It has also been used to study its effect on lipopolysaccharide (LPS)-induced microglial activation
Tamoxifen is a Protein kinase C inhibitor. It induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.

Codice catalogo: (ABCAAB141943-25)

Fornitore: Abcam

Codice articolo fornitore: AB141943-25

Codice articolo locale: ABCAAB141943-25

Descrizione: (Z)-4-HYDROXYTAMOXIFEN 1 * 25 mg

UOM: 1 * 25 mg

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 This is a MarketSource item. Additional charges may apply

Codice catalogo: (ABCAAB143637-5)

Fornitore: Abcam

Codice articolo fornitore: AB143637-5

Codice articolo locale: ABCAAB143637-5

Descrizione: (E)-4-HYDROXYTAMOXIFEN 1 * 5 mg

UOM: 1 * 5 mg

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 This is a MarketSource item. Additional charges may apply

Codice catalogo: (ABCAAB143637-25)

Fornitore: Abcam

Codice articolo fornitore: AB143637-25

Codice articolo locale: ABCAAB143637-25

Descrizione: (E)-4-HYDROXYTAMOXIFEN 1 * 25 mg

UOM: 1 * 25 mg

Promo

 This is a MarketSource item. Additional charges may apply

Codice catalogo: (ABCAAB141943-10)

Fornitore: Abcam

Codice articolo fornitore: AB141943-10

Codice articolo locale: ABCAAB141943-10

Descrizione: (Z)-4-HYDROXYTAMOXIFEN 1 * 10 mg

UOM: 1 * 10 mg

Promo

 This is a MarketSource item. Additional charges may apply

Codice catalogo: (ABCAAB141943-5)

Fornitore: Abcam

Codice articolo fornitore: AB141943-5

Codice articolo locale: ABCAAB141943-5

Descrizione: (Z)-4-HYDROXYTAMOXIFEN 1 * 5 mg

UOM: 1 * 5 mg

Promo

 This is a MarketSource item. Additional charges may apply

Codice catalogo: (ABCAAB143637-10)

Fornitore: Abcam

Codice articolo fornitore: AB143637-10

Codice articolo locale: ABCAAB143637-10

Descrizione: (E)-4-HYDROXYTAMOXIFEN 1 * 10 mg

UOM: 1 * 10 mg

Promo

 This is a MarketSource item. Additional charges may apply

Codice catalogo: (ABCAAB143638-25)

Fornitore: Abcam

Codice articolo fornitore: AB143638-25

Codice articolo locale: ABCAAB143638-25

Descrizione: (E,Z)-4-HYDROXYTAMOXIFEN (17197F0KYM) 1 * 25 mg

UOM: 1 * 25 mg

Promo

 This is a MarketSource item. Additional charges may apply

Fornitore: MP Biomedicals

Descrizione: Tamoxifen has been shown to protect bone from estrogen-deficiency bone loss and lower plasma cholesterol in the rat. A 10 µM solution has exhibited fungicidal activity (optimal pH 7,5) against yeast cells of C. albicans. It has been implemented in liver carcinogenesis in rats.