Iodoacetamide 98% stabilizzato
Fornitore: Thermo Scientific
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Pericolo
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Synonyms:
2-Iodoacetamide
Stabilization:
stabilizzata con idrato ∼5-8%
Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation.
2-Iodoacetamide is used as an electrophile for covalent modification of nucleophilic residues on proteins such as cysteine, methionine and histidine. It is used to bind with thiol group of cysteine, thereby it protects the formation disulfide bonds. It is involved as an inhibitor of deubiquitinase enzymes (DUBs). Further, it acts as an alkylating sulfhydryl reagent.
Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation
Formula:
ICH₂CONH₂ Peso molecolare: 184,96 g/mol Punto di ebollizione: 266 °C (1013 hPa) Punto di fusione: 92…95 °C (dried) Temperatura di stoccaggio: Refrigerata |
MDL Number:
MFCD00008028 CAS Number: 144-48-9 EINECS: 205-630-1 UN: 2811 ADR: 6.1,III |
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