Methanol 99,5 GC_ASSAY_METHOD, EMPROVE® ESSENTIAL NF, Ph. Eur., BP, JPE, extra_pure suitable for use as excipient, SAFC®
Fornitore: MERCK PRODUCTION CHEMICALS
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Pericolo
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Synonyms:
Alcol metilico, Alcol denaturato
For full details of specification and hazards please see www.vwr.com or the VWR Chemicals catalogues
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities).
Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Conforms to Ph Eur, BP, JPE, NF
Formula:
CH₃OH Peso molecolare: 32.04 g/mol Punto di ebollizione: 64.6 Punto di fusione: –98 °C Densità: 0.7918 g/cm³ (20 °C) Flash Pt: 9.7 °C Temperatura di stoccaggio: Ambiente |
MDL Number:
MFCD00004595 CAS Number: 67-56-1 EINECS: 200-659-6 UN: 1230 ADR: 3 (6.1) II REACH: 01-2119433307-44 Merck Index: 13,05984 |
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Risultati del test di specificazione
Assay (GC) | ≥ 99.5 % |
Identity (IR) | conforms |
Identity B (NF) | conforms |
Identity (JPE) | conforms |
Appearance | conforms |
Clarity of solution | conforms |
Acidity or alkalinity | conforms |
Acidity | conforms |
Alkalinity (as NH₃) | ≤ 3 ppm |
Refractive index (n 20/D) | 1.328 - 1.330 |
Density (d 20 °C/20 °C) | 0.791 - 0.793 |
Boiling range (64-65°C) | ≥ 95 % (v/v) |
Absorbance (at 230 nm) | ≤ 0.150 |
Absorbance (at 250 nm) | ≤ 0.050 |
Absorbance (at 270 nm) | ≤ 0.020 |
Absorbance (at 290 nm) | ≤ 0.010 |
The absorption curve is smooth | conforms |
Benzene (impurity A) (GC) | ≤ 2 ppm |
Acetone (GC) | ≤ 0.001 % |
Ethanol (GC) | ≤ 0.005 % |
Ethanol (JPE) | conforms |
Related substances (GC) | conforms |
Residual solvents class 3 (ICH Q3C) | < 0.5 |
Other residual solvents (ICH Q3C) | excluded by manufacturing process |
Al (Aluminium)* | ≤ 0.05 ppm |
Cu (Copper)* | ≤ 0.05 ppm |
Zn (Zinc)* | ≤ 0.05 ppm |
Heavy metals | conforms |
Aldehydes and Acetone (as acetone) | ≤ 0.003 % |
Aldehyde and other foreign reducing substances | conforms |
Reducing substances | conforms |
Readily oxidizable substances | conforms |
Readily carbonizable substances | conforms |
Readily carbonizable substances (JPE) | conforms |
Evaporation residue | ≤ 0.0010 % |
Water | ≤ 0.10 % |
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