Mycophenolate mofetil ≥98% (by HPLC), white to off-white solid
Fornitore: ENZO LIFE SCIENCES AG
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Attenzione
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Synonyms:
2-Morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoate, 2-(4-Morpholinyl)ethyl (E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoate, (E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic Acid 2-(4-Morpholinyl)ethyl Ester
Immunosuppressant. Isolated from Penicillium brevicompactum.
Mycophenolate mofetil (cellcept) is an immunosuppressant prodrug of mycophenolic acid, a fermentation product of Penicillium brevicompactum. Immunosuppression occurs via inhibition of type II inosine-5’-monophosphate dehydrogenase, depleting guanosine preferentially in T and B lymphocytes. Mycophenolic acid displays anti-inflammatory activity by preventing NO production specifically from iNOS and by blocking glycosylation and expression of adhesion molecules and therefore recruitment of lymphocytes and monocytes to sites of inflammation.
Soluble in DMSO (25 mg/ml) or 100% ethanol (25 mg/ml, warm).
Formula:
C₂₃H₃₁NO₇ Peso molecolare: 433,50 g/mol |
MDL Number:
MFCD00867568 CAS Number: 128794-94-5 UN: 3077 ADR: 9,III |
Risultati del test di specificazione
Purity | ≥98% (HPLC) |
Appearance | White to off-white solid |
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