Indirubin-3'-oxime ≥98%
Fornitore: ENZO LIFE SCIENCES AG
Synonyms:
3-(Hydroxyimino)-[2,3'-biindolinylidene]-2'-one, Indirubin-3'-monoxime
A potent inhibitor of glycogen synthase kinase-3β (IC50=22 nM). Also inhibits CDK1 (p34cdc2; IC50=180 nM) and CDK5 (IC50=100 nM). It reversibly arrests asynchronous HBL-100 cells at G2. Induces apoptosis in the mammary carcinoma cell line MCF-7 (10 µM).
- Inhibitor of CDK and GSK
Dark red solid.
Soluble in DMSO (6mg/ml) and ethanol (4mg/ml).
Formula:
C₁₆H₁₁N₃O₂ Peso molecolare: 277,283 g/mol Temperatura di stoccaggio: Congelamento |
MDL Number:
MFCD02683594 CAS Number: 160807-49-8 |
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