(R)-Roscovitine ≥95% (by TLC)
Fornitore: ENZO LIFE SCIENCES AG
Synonyms:
2-(R)-(1-Ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine, Roscovitine, (R)-2-((6-(Benzylamino)-9-isopropyl-9H-purin-2-yl)amino)butan-1-ol
CDK inhibitor
Potent and selective inhibitor of CDKs. Selective for CDK1/cyclin B kinase (IC50=450nM) [2], CDK2 (IC50=700nM) [4] and CDK5/p35 (IC50=160nM) [4,5]. More potent than olomoucine (Prod. No. BML-CC200). Inhibits M phase promoting factor (MPF) kinase activity. Has effects on calcium channel gating.
Formula:
C₁₉H₂₆N₆O Peso molecolare: 354,45 g/mol |
MDL Number:
MFCD02266401 CAS Number: 186692-46-6 |
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