SKF-96365 hydrochloride ≥98% (by HPLC)
Fornitore: ENZO LIFE SCIENCES AG
Synonyms:
1-(2-(4-Methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole hydrochloride, 1-[2-(4-Methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl]-1H-imidazole hydrochloride, SKF-96365
A novel, selective inhibitor of receptor-mediated calcium entry. It inhibits receptor-mediated calcium entry in stimulated platelets (IC50=8-12µM) neutrophils and endothelial cells at concentrations which do not affect internal Ca²⁺ release. Note, in some cells SK&F 96365 can activate a novel Ca²⁺ entry pathway. Blocks TRPC3 and TRPC6 activation. Inhibits the histamine-induced formation of nitric oxide in human endothelial cells.
- TRP channel blocker
White solid.
Soluble in water (30mg/ml).
Formula:
C₂₂H₂₆N₂O₃·HCl Peso molecolare: 402,9 g/mol Punto di fusione: 117…119 °C Temperatura di stoccaggio: Ambiente |
MDL Number:
MFCD00236407 CAS Number: 130495-35-1 |
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