Sulindac Sulphide ≥99% (by TLC)
Fornitore: ENZO LIFE SCIENCES AG
Active metabolite of sulindac. Inhibits cyclooxygenase. More selective for PGHS-1 (ID50=0.5 µM) over PGHS-2 (ID50=14 µM). Induces apoptosis by a cyclooxygenase-independent mechanism. Inhibits colorectal cancer growth and γ-secretase. NF-κB inhibitor. Inhibits Ras signaling.
- COX inhibitor
Yellow-orange solid.
Soluble in DMSO (>25mg/ml) or 100% ethanol (5mg/ml, warm).
Formula:
C₂₀H₁₇FO₂S Peso molecolare: 340,4 g/mol Temperatura di stoccaggio: Ambiente |
MDL Number:
MFCD00869764 CAS Number: 32004-67-4 |
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