GYY 4137 ≥95%
Fornitore: ENZO LIFE SCIENCES AG
H2S donor
Water-soluble, slow-releasing hydrogen sulfide (H2S) donor. Shows vasodilator and antihypertensive activity in rats in both acute (L-NAME-induced) or chronic (spontaneously hypertensive) hypertension models. Inhibits LPS-induced release of various proinflammatory mediators (such as IL-1β, IL-6, TNF-α, nitric oxide (NO) and PGE2) in RAW264.7 cells. Increases the synthesis of the anti-inflammatory chemokine IL-10 through NF-κB, ATF-2 and HSP27 dependent pathways in RAW264.7 cells.
Synthetic.
Formula:
C₁₁H₁₆NO₂PS₂·C₄H₉NO Peso molecolare: 288,4·87,1 g/mol |
CAS Number:
106740-09-4 |
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