Streptozocina ≥97%
Fornitore: ENZO LIFE SCIENCES AG
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Pericolo
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Synonyms:
1-Methyl-1-nitroso-3-((2S,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)urea, Streptozotocin
Widely used diabetes inducer in rodents. Inhibition of β-cell O-GlcNAcase by streptozotocin is the mechanism that accounts for its diabetogenic toxicity. N-nitroso-containing antibiotic, acting as a nitric oxide (NO) donor and vasorelaxant. Relaxes phenylephrine-contracted aortic rings at 10µM. Potent methylating agent for DNA.
- O-GlcNAcase inhibitor
White to pale yellow crystalline solid.
Soluble in water (nH2O at 102.8mg/ml) or 100% ethanol (200 proof at 0.92mg/ml).
Formula:
C₈H₁₅N₃O₇ Peso molecolare: 265,2 g/mol Temperatura di stoccaggio: Congelamento |
MDL Number:
MFCD00006607 CAS Number: 18883-66-4 EINECS: 242-646-8 |
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