Rotenone ≥98% (by HPLC)
Fornitore: ENZO LIFE SCIENCES AG
Insecticide. Inhibitor of mitochondrial electron transport. Specifically inhibits NAD-linked substrate oxidation at the oxygen side of NADH dehydrogenase (EC50=10pmol/mg). Inhibits mammalian cell proliferation by inhibiting microtubule assembly through tubulin binding. Can inhibit mitochondrial swelling and cytochrome c release induced by N-methyl-4-phenylpyridinium.
Synthetic. Originally isolated from Lonchocarpus sp. or Derris sp.
Formula:
C₂₃H₂₂O₆ Peso molecolare: 394,42 g/mol |
MDL Number:
MFCD09025614 CAS Number: 83-79-4 |
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