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(S)-(+)-Camptothecin ≥98%

Fornitore: ENZO LIFE SCIENCES AG

Synonyms: (S)-4-Ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, (+)-Camptothecin, 4-Ethyl-4-hydroxy-1H-pyrano-[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

ALX350015G001 ALX350015M050 ALX350015M250
ENZOALX350015G001EA 667.7 EUR
ENZOALX350015G001 ENZOALX350015M050 ENZOALX350015M250
(S)-(+)-Camptothecin ≥98%
(S)-(+)-Camptothecin

Potent antitumor agent


Potent antitumor agent. Inhibitor of DNA-topoisomerase I. Activates p53 resulting in upregulated expression of TRAIL-R2 (DR5) and Bak to overcome TRAIL resistance in Bax-deficient human colon carcinoma cells. Inhinbits Tat-mediated transactivation of HIV-1. Induces apoptosis in osteosarcoma and hepatoma cells. Suppresses nitric oxide (NO) biosynthesis.


Isolated from Mappia foetida Miers (Nothapodytes foetida (Wt.) Sleumer).

Formula: C₂₀H₁₆N₂O₄
Peso molecolare: 348,36 g/mol
MDL Number: MFCD00081076
CAS Number: 7689-03-4

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