BAY 61-3606 hydrochloride ≥98% (by HPLC)
Fornitore: ENZO LIFE SCIENCES AG
Syk inhibitor
Cell permeable, potent, ATP-competitive and reversible inhibitor of spleen tyrosine kinase (Syk) (IC50=10nM). Highly selective if compared to other kinases; shows no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src up to concentrations of 4.7µM. Anti-inflammatory and orally active. Exhibits good in vivo efficacy in the treatment of various allergy and asthma conditions in rat models.
Formula:
C₂₀H₁₈N₆O₃·HCl |
CAS Number:
732938-37-8 |
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