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SB 225002 ≥98% (by HPLC)

Fornitore: ENZO LIFE SCIENCES AG

Synonyms: SB225002, 1-(2-Bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea

ALX270478M001 ALX270478M005
ENZOALX270478M001EA 60.5 EUR
ENZOALX270478M001 ENZOALX270478M005
SB 225002 ≥98% (by HPLC)
SB 225002

Chemokine receptor ligand


Potent and selective antagonist of CXCR2 chemokine receptor (IC50=22nM). >150-fold more selective over CXCR1 receptor. Inhibits IL-8- (IC50=8nM) and GROα-mediated (IC50=10nM) calcium mobilisation. Prevents IL-8-induced neutrophil migration. Inhibits HIV replication in lymphocytes and macrophages.

Formula: C₁₃H₁₀BrN₃O₄
Peso molecolare: 352,10 g/mol
MDL Number: MFCD00954637
CAS Number: 182498-32-4

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