Compound 15e ≥99% (by HPLC)
Fornitore: ENZO LIFE SCIENCES AG
Synonyms:
PI3K-α Inhibitor, 3-(4-Morpholinothieno[3,2-d]pyrimidin-2-yl)phenol
PI3 kinase inhibitor
Potent and specific inhibitor of phosphoinositide 3-kinasep110alpha isoform (IC50=0.0020µM). p110beta isoform (IC50=0.016µM)p110gamma isoform (IC50=0.66µM)C2beta isoform (IC50=0.22µM). Inhibits proliferation of A375 melanoma cells (IC50=0.58µM). Inhibits proliferation of U87MG human glioblastoma cells (IC50=1.10.µM).Inhibits proliferation of A2780 human ovarian cells (IC50=0.27µM).
Formula:
C₁₆H₁₅N₃O₂S Peso molecolare: 313,4 g/mol |
CAS Number:
371943-05-4 |
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