AS601245 sum of isomers ≥95% (by HPLC)
Fornitore: ENZO LIFE SCIENCES AG
Synonyms:
2-(Benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)amino)pyrimidin-4-yl)acetonitrile
Jnk inhibitor
Potent and cell permeable ATP competitive JNK inhibitor (hJNK1: IC50=150nM, hJNK2: IC50=220nM and hJNK3: IC50=70 nM). Displays anti-inflammatory properties and has been shown to reduce TNF-α plasma levels induced by LPS in mice.
Formula:
C₂₀H₁₆N₆S Peso molecolare: 372,45 g/mol |
MDL Number:
MFCD07772196 CAS Number: 345987-15-7 |
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