PJ-34 hydrochloride (sintetico) ≥98% (by HPLC)
Fornitore: ENZO LIFE SCIENCES AG
Synonyms:
2-(Dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridin-2-yl)acetamide hydrochloride, PJ34 HCl
Potent, water soluble poly(ADP-ribose) polymerase (PARP) inhibitor (EC50=20nM compared to EC50=200µM of the prototypical PARP inhibitor 3-aminobenzamide). Inhibits peroxynitrite-induced cell necrosis (EC50=20nM). Has significant, dose-dependent, anti-inflammatory effects in a variety of local inflammation models and provides cardioprotection by decreasing myocardial infarct size.
- PARP inhibitor
White to light brown or yellow powder.
Soluble in DMSO (up to 30 mg/ml) or water (up to 20 mg/ml).
Formula:
C₁₇H₁₇N₃O₂·HCl Peso molecolare: 295,2·36,5 g/mol Temperatura di stoccaggio: Refrigerata |
MDL Number:
MFCD22581510 CAS Number: 344458-15-7 |
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