Alsterpaullone ≥95%
Fornitore: ENZO LIFE SCIENCES AG
Synonyms:
7,12-Dihydro-9-nitroindolo[3,2-d][1]benzazepin-6(5H)-one
Inhibitor of CDK and GSK
Potent inhibitor of CDK1/cyclin B (IC50=35nM). Potent and selective inhibitor of CDK2/cyclin A, CDK2/cyclin E (IC50=200nM), CDK5/p25 (IC50=40nM), CDK5/p35 (IC50=40nM) and GSK-3β . Induces apoptosis by activation of caspase-8 and caspase-9 followed by disruption of the mitochondrial potential.Licensed from NCI.
Formula:
C₁₆H₁₁N₃O₃ Peso molecolare: 293,3 g/mol |
MDL Number:
MFCD02683579 CAS Number: 237430-03-4 |
Learn more
About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...