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Alsterpaullone ≥95%

Fornitore: ENZO LIFE SCIENCES AG

Synonyms: 7,12-Dihydro-9-nitroindolo[3,2-d][1]benzazepin-6(5H)-one

ALX270275M001 ALX270275M005
ENZOALX270275M001EA 105.6 EUR
ENZOALX270275M001 ENZOALX270275M005
Alsterpaullone ≥95%
Alsterpaullone

Inhibitor of CDK and GSK


Potent inhibitor of CDK1/cyclin B (IC50=35nM). Potent and selective inhibitor of CDK2/cyclin A, CDK2/cyclin E (IC50=200nM), CDK5/p25 (IC50=40nM), CDK5/p35 (IC50=40nM) and GSK-3β . Induces apoptosis by activation of caspase-8 and caspase-9 followed by disruption of the mitochondrial potential.Licensed from NCI.

Formula: C₁₆H₁₁N₃O₃
Peso molecolare: 293,3 g/mol
MDL Number: MFCD02683579
CAS Number: 237430-03-4

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