Purvalanol A ≥99% (by NMR)
Fornitore: ENZO LIFE SCIENCES AG
Synonyms:
6-[(3-Chloro)anilino]-2(1R)-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine, (R)-2-((6-((3-Chlorophenyl)amino)-9-isopropyl-9H-purin-2-yl)amino)-3-methylbutan-1-ol
Inhibitor of human CDK1 (IC50=4nM), CDK2/cyclin A (IC50=70nM), Cdc2/cyclin B, CDK2/cyclin E (IC50=35nM), CDK4/cyclin D1 (IC50=850nM) as well as CDK5/p35 (IC50=75nM). More membrane permeable than purvalanol B.
- CDK/cyclin inhibitor
Off-white to yellow powder.
Soluble in DMSO, methanol or dichloromethane.
Formula:
C₁₉H₂₅N₆OCl Peso molecolare: 388,9 g/mol Temperatura di stoccaggio: Congelamento |
MDL Number:
MFCD02179211 CAS Number: 212844-53-6 |
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