STAT3 Inhibitor V, Stattic ≥98% (by TLC)
Fornitore: ENZO LIFE SCIENCES AG
Synonyms:
Stattic, Stat3 Inhibitor V, 6-Nitrobenzo[b]thiophene 1,1-dioxide, 6-Nitro-1,1-dioxide-benzo[b]thiophene, 6-Nitro[b]thiophene-1,1-dioxide
Small molecule STAT3-specific inhibitor which blocks activation, dimerization and nuclear translocation via binding to the STAT3 SH2 domain. It is a very useful tool for exploring STAT3-mediated signaling pathways. It blocks LPS-mediated STAT3 tyrosine phosphorylation which leads to inhibition of LPS-mediated IL-1β and IL-6 production. In primary cultures of rat neural stem cells it blocks IL-15-induced differentiation.
- STAT inhibitor
Pale yellow solid.
Soluble in DMSO (>25 mg/ml), 100% ethanol (10 mg/ml).
Formula:
C₈H₅NO₄S Peso molecolare: 211,19 g/mol Temperatura di stoccaggio: Ambiente |
MDL Number:
MFCD00173799 CAS Number: 19983-44-9 |
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