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Dorsomorphin ≥98% (by TLC)

Fornitore: ENZO LIFE SCIENCES AG

Synonyms: 6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine, 6-[4-(2-Piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine

BMLEI3690005 BMLEI3690025
ENZOBMLEI3690005EA 110 EUR
ENZOBMLEI3690005 ENZOBMLEI3690025
Dorsomorphin ≥98% (by TLC)
Dorsomorphin

Cell-permeable pyrrazolopyrimidine derivative that inhibits AMP kinase (Ki=109nM in the absence of AMP) in an ATP-competitive manner. It displays no significant inhibition of ZAPK, SYK, PKCT, PKA and JAK3. Decreases food intake in mice and inhibits the effects of AICAR and metformin. It has been shown to inhibit BMP type I receptors ALK2, ALK3 and ALK6. Promotes cardiomyogenesis in mouse embryonic stem cells. Induces protective autophagy in cancer cell lines.


  • AMPK inhibitor


Yellow solid.


Soluble in DMSO (3mg/ml, warm)

Formula: C₂₄H₂₅N₅O
Peso molecolare: 399,5 g/mol
Temperatura di stoccaggio: Congelamento
MDL Number: MFCD08705402
CAS Number: 866405-64-3
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