SC-514 ≥98% (by TLC)
Fornitore: ENZO LIFE SCIENCES AG
Synonyms:
4-amino-[2,3'-bithiophene]-5-carboxamide, IKK-2 Inhibitor, SC-514
IKK inhibitor
Selective, reversible and ATP-competitive inhibitor of IKK2 (IC50=11.2µM). Does not inhibit other IKK isoforms or other serine/threonine or tyrosine kinases. Inhibits transcription of NF-κB dependent genes in IL-1β-induced rheumatoid arthritis-derived synovial fibroblasts in a dose-dependent fashion.
Formula:
C₉H₈N₂OS₂ Peso molecolare: 224,3 g/mol |
MDL Number:
MFCD00206459 CAS Number: 354812-17-2 |
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