AG-879 ≥99%
Fornitore: ENZO LIFE SCIENCES AG
Synonyms:
Tyrphostin AG 879, (E)-2-Cyano-3-(3,5-di-tert-butyl-4-hydroxyphenyl)prop-2-enethioamide
NGF receptor inhibitor
AG-879, a member of the tyrphostin family of tyrosine kinase inhibitors, inhibits NGF receptor (pp140c-trk) autophosphorylation selectively with no inhibition of EGF or PDGF receptor phosphorylation (IC50=10 µM). AG-879 inhibits NGF-induced neurite outgrowth in PC12 cells.
Formula:
C₁₈H₂₄N₂OS Peso molecolare: 316,4610 g/mol |
MDL Number:
MFCD00236450 CAS Number: 148741-30-4 |
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