Ro 41-5253 ≥98% (by TLC)
Fornitore: ENZO LIFE SCIENCES AG
Retinoic acid receptor ligand
A selective RARα antagonist (concentration required to inhibit 50% of specific retinoic acid binding: RARα, 60 nM; RARß, 2400 nM; RARτ, 3300 nM). Counteracts the effects of retinoic acid on HL-60 cell differentiation, B-lymphocyte polyclonal activation and in a RARα transactivation assay. Ro 41-5253 suppresses retinoic acid-induced connexin 43 protein expression in 10T1/2 cells.
CAS Number:
144092-31-9 |
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