H-7 dihydrochloride ≥98% (by TLC)
Fornitore: ENZO LIFE SCIENCES AG
Synonyms:
5-((2-Methylpiperazin-1-yl)sulphonyl)isoquinoline dihydrochloride, Protein kinase inhibitor H-7 2HCl
Inhibits PKA (Ki=3.0μM), PKG (Ki=5.8μM), MLCK (Ki=97μM) and PKC (Ki=6μM). Also inhibits myosin light chain kinase. Induces apoptotic DNA fragmentation and cell death. Inhibits telomerase activity in treated NPC-076 cells. Cell permeable.
- PKC inhibitor
White to light yellow solid.
Soluble in water (50mg/ml), 100% ethanol or DMSO.
Formula:
C₁₄H₁₇N₃O₂S·2HCl Peso molecolare: 364,29 g/mol Punto di fusione: 219…222 °C Temperatura di stoccaggio: Refrigerata |
MDL Number:
MFCD00036961 CAS Number: 108930-17-2 |
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