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PP1 ≥98% (by TLC)

Fornitore: ENZO LIFE SCIENCES AG

Synonyms: 1-(tert-Butyl)-3-(p-tolyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

BMLEI2750001 BMLEI2750005
ENZOBMLEI2750001EA 110 EUR
ENZOBMLEI2750001 ENZOBMLEI2750005
PP1 ≥98% (by TLC)
PP1

Src kinase inhibitor


A highly potent and selective inhibitor of Src family tyrosine kinases, IC50=5 nM for p56lck; p59fynT=6 nM; p60src=170 nM. Inhibition of Src family kinases by PP1 has been shown to: prevent a-thrombin-stimulated Akt phosphorylation, delay PAF-mediated STAT3 phosphorylation, block Zn2+-induced Ras activation, block adhesion-dependent tyrosine phosphorylation of p105HEF1 5, and inhibit HLA-DR-induced tyrosine phosphorylation without affecting the activation of ERK1/2.

Formula: C₁₆H₁₉N₅
Peso molecolare: 281,4 g/mol
MDL Number: MFCD01076570
CAS Number: 172889-26-8
https://digitalassets.avantorsciences.com/adaptivemedia/rendition?id=e1143900eb5c46847ca41de6e2f432420e8f0eac&vid=3d9694521b8884f868a020e3f8798ce3990c43d0&prid=web&clid=SAPDAM

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