Fumagillin ≥95% (by TLC)
Fornitore: ENZO LIFE SCIENCES AG
Synonyms:
(2E,4E,6E,8E)-10-(((3R,4S,5S,6R)-5-methoxy-4-((2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl)-1-oxaspiro[2.5]octan-6-yl)oxy)-10-oxodeca-2,4,6,8-tetraenoic acid
Methionine aminopeptidase 2 inhibitor
Inhibitor of angiogenesis and endothelial cell proliferation. Specific inhibitor of methionine aminopeptidase type II (MetAP-II) by covalently modifying a conserved active-site histidine. Precursor to TNP-470. Exhibits antitumor activity in estrogen-induced pituitary adenoma. Antineoplastic. Anti-infective.
Isolated from Aspergillus fumigatus.
Formula:
C₂₆H₃₄O₇ Peso molecolare: 458,551 g/mol |
MDL Number:
MFCD03990453 CAS Number: 23110-15-8 |
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