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Calpeptin ≥98% (by TLC)

Fornitore: ENZO LIFE SCIENCES AG

Synonyms: benzyl N-[(2S)-4-methyl-1-oxo-1-[[(2S)-1-oxohexan-2-yl]amino]pentan-2-yl]carbamate, Cbz-Leu-Nle-al, Benzyl ((S)-4-methyl-1-oxo-1-(((S)-1-oxohexan-2-yl)amino)pentan-2-yl)carbamate

BMLPI1010010 BMLPI1010050
ENZOBMLPI1010010EA 136.4 EUR
ENZOBMLPI1010010 ENZOBMLPI1010050
Calpeptin ≥98% (by TLC)
Calpeptin

Calpain and cathepsin inhibitor


Membrane permeable inhibitor of calpain I and II, cathepsin L and cathepsin K (IC50=0.11 nM). Promotes neurite elongation in differentiating PC12 cells. Prevents Ca2+-ionophore induced degradation of actin binding protein and P235 in platelets. Inhibits myosin light chain phosphorylation in platelets stimulated by collagen, ionomycin (Prod. No. ALX-450-006) or thrombin. Inhibits LPS induced iNOS transcription and NF-kappaB activation, possibly via proteasome inhibition.

Formula: C₂₀H₃₀N₂O₄
Peso molecolare: 362,47 g/mol
MDL Number: MFCD00155623
CAS Number: 117591-20-5
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