U-18666A ≥99%
Fornitore: ENZO LIFE SCIENCES AG
Oxido-squalene cyclase inhibitor
A useful tool for inhibition of cholesterol transport from late endosomes/lysosomes to the endoplasmic reticulum. Inhibits cholesterol transport in a variety of cell types such as macrophages and sympathetic neurons. May be used to induce a Neimann-Pick disease type C (NPC)or NPC-like phenotype in a variety of cell types. Inhibits cholesterol biosynthesis at the level of oxido-squalene cyclase (OSC). Induction of cataracts is a common toxic feature of OSC inhibitors such as U18666A.
Formula:
C₂₅H₄₂ClNO₂ Peso molecolare: 424,066 g/mol |
MDL Number:
MFCD00210908 CAS Number: 3039-71-2 |
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