β-Lapachone ≥98%
Fornitore: ENZO LIFE SCIENCES AG
Synonyms:
2,2-Dimethyl-3,4-dihydro-2H-benzo[h]chromene-5,6-dione
Topoisomerase inhibitor
Novel DNA topoisomerase I inhibitor. Unlike camptothecin, beta-lapachone does not stabilize the cleavable complex, indicating a novel mode of action. Induces apoptosis in HL-60 and human prostate cancer cells via a p53-independent mechanism and blocks the cell cycle at G0/G1.
Formula:
C₁₅H₁₄O₃ Peso molecolare: 242,274 g/mol |
MDL Number:
MFCD01712233 CAS Number: 4707-32-8 |
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