A-803467 ≥98%
Fornitore: ENZO LIFE SCIENCES AG
Synonyms:
5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide
Na+ channel blocker
A-803467 is a potent and selective inhibitor of the TTX-resistant voltage-gated sodium channel Nav1.8 which is preferentially expressed on sensory neurons. IC50 for human Nav1.8=8.0 nM (140 nM for rat). It attenuates neuropathic and inflammatory pain in various animal models.
Formula:
C₁₉H₁₆ClNO₄ Peso molecolare: 357,79 g/mol |
MDL Number:
MFCD10574689 CAS Number: 944261-79-4 |
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