ZM-336372 ≥95% (by HPLC)
Fornitore: ENZO LIFE SCIENCES AG
Synonyms:
3-(Dimethylamino)-N-(3-(4-hydroxybenzamido)-4-methylphenyl)benzamide, ZM 336372
Potent and specific inhibitor of the protein kinase c-Raf (IC50=70nM). Has no significant effect on many other protein kinases tested (even at 50µM) with the exception of p38 (SAPK2a) (IC50=2µM) and SAPK2b (p38β) (IC50=2µM). Induces a paradoxical >100-fold activation of c-Raf in whole cells.
- Raf inhibitor
White to off-white solid.
Soluble in DMSO (200mg/ml).
Formula:
C₂₃H₂₃N₃O₃ Peso molecolare: 389,455 g/mol Temperatura di stoccaggio: Congelamento |
MDL Number:
MFCD02683971 CAS Number: 208260-29-1 |
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