DSG (Disuccinimidyl glutarate), Pierce™
Fornitore: Thermo Fisher Scientific
Synonyms:
DSG
Thermo Scientific Pierce DSG is a water-insoluble, homo-bifunctional N-hydroxysuccinimide ester (NHS-ester) crosslinker often used for conjugating radiolabeled ligands to cell-surface receptors. The NHS ester is the simplest and most commonly used reactive group for crosslinking and labeling proteins and peptides. NHS esters react with primary amines on the N-termini of peptides and the amine of lysine residues, forming a stable, covalent amide bond and releasing the NHS group.
- Reactive groups: NHS ester (both ends)
- Reactive towards: amino groups (primary amines)
- Non-cleavable
- Water-insoluble (dissolve first in DMF or DMSO)
- Membrane-permeable, allowing for intracellular crosslinking
- Can increase crosslinking efficiency compared to DSS in some applications
Thermo Scientific No-Weigh products are specialty reagents provided in a pre-aliquoted format. The pre-weighed packaging prevents the loss of reagent reactivity and contamination over time by eliminating the repetitive opening and closing of the vial. The format enables use of a fresh vial of reagent each time, eliminating the hassle of weighing small amounts of reagents and reducing concerns over reagent stability.
Attenzione: For Research Use Only. Not for use in diagnostic procedures.
Formula:
C₁₃H₁₄N₂O₈ Peso molecolare: 326,26 g/mol Temperatura di stoccaggio: Refrigerata |
MDL Number:
MFCD00153597 CAS Number: 79642-50-5 |
Risultati del test di specificazione
Product Line | Pierce™ |
Labeling Method | Chemical Labeling |
Crosslinker Type | Homobifunctional |
Reactive Moiety | NHS Ester |
Spacer | Short |
Form | Powder |
Quantity | 50 mg/10 x 1 mg |
Type | Crosslinker |
Solubility | DMF, DMSO |
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