Sorafenib (BAY 43-9006)
Fornitore: Apollo Scientific
Synonyms:
4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide, Sorafenib, N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[4-[2-(N-methylcarbamoyl)-4-pyridyloxy]phenyl]urea, 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide
Sorafenib is a multikinase inhibitor of Raf-1 B-Raf and VEGFR-2 with IC50 of 6 nM 22 nM and 90 nM in cell-free assays respectively.
Formula:
C₂₁H₁₆ClF₃N₄O₃ Peso molecolare: 464,82 g/mol Punto di fusione: 197 °C Densità: 1,46 g/cm³ (25 °C) Temperatura di stoccaggio: Refrigerata |
MDL Number:
MFCD06411450 CAS Number: 284461-73-0 UN: 3077 ADR: 9+EHS,III |
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