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α-Toluenesulfonilfluoruro, white to off white needle crystals

Fornitore: MP Biomedicals
Pericolo

Synonyms: Fenilmetansolfonil fluoruro

02195381.2 0219538180 0219538101 0219538105 0219538125
ICNA02195381.2EA 22.9 EUR
ICNA02195381.2 ICNA0219538180 ICNA0219538101 ICNA0219538105 ICNA0219538125
α-Toluenesulfonilfluoruro, white to off white needle crystals
α-Toluenesulfonilfluoruro

Phenylmethylsulfonyl fluoride is an irreversible inhibitor of serine proteases - inhibits trypsin, chymotrypsin and protease. Inhibits mammalian acetyl cholinesterase, but not those from fish sources.


  • Presentation: White to off white needle crystals
  • Causes sulfonylation of the active-site serine residue
  • A less toxic substitute for the extremely toxic diisopropylfluorophosphate


Phenylmethylsulfonyl fluoride inhibits serine proteases such as trypsin and chymotrypsin. Also inhibits cysteine proteases (reversible by reduced thiols) and mammalian acetylcholinesterase.
Administration of PMSF produces analgesia unrelated to its anticholinesterase effect, and prolongs the analagesic effect of centrally administered β-endorphin.


Soluble in methanol and ethanol

Formula: C₇H₇FO₂S
Peso molecolare: 174,2 g/mol
Punto di ebollizione: 80 - 85 °C (0,3 -rr)
Punto di fusione: 89…99 °C
Temperatura di stoccaggio: Refrigerata
MDL Number: MFCD00007424
CAS Number: 329-98-6
EINECS: 206-350-2
UN: 2928
ADR: 6.1,II

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