Q-VD-OPh
Fornitore: Cayman Chemical
Q-VD-OPH is a broad-spectrum caspase inhibitor, blocking caspases-3, -7, -8, -9, -10, and -12 and inhibiting apoptosis when used at 10 µm. It more effectively inhibits apoptosis and is much less cytotoxic than Z-VAD-FMK and Boc-D-FMK.
- Substance complement: Tautomers mixture
- GHS symbols and signal word: GHS05, GHS07, GHS08 and Danger
Q-VD-OPH can be used in vivo, to prevent ischemia-reperfusion injury-induced apoptosis. This compound broadly inhibiting caspases, also promotes the differentiation of leukemic blasts cells, suggesting an application in differentiation therapy of certain forms of cancer.
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