Dexmedetomidine hydrochloride ≥99%
Fornitore: Cayman Chemical
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Attenzione
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Synonyms:
Dex, (S)-Medetomidine hydrochloride, (+)-Medetomidine hydrochloride, (S)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride, (S)-4-(α,2,3-Trimethybenzyl)-1H-imidazole hydrochloride, Precedex, 5-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride
Dexmedetomidine is the (S)-enantiomer of medetomidine, an imidazole compound that binds to α2-adrenoceptors (Ki = 1.08 nM) with high affinity and selectivity compared to that of α1-adrenoceptors (Ki = 1.8 μM). Dexmedetomidine produces analgesic, sedative, and anxiolytic effects through both presynaptic activation of α2-adrenoceptors, which inhibits norepinephrine release, and postsynaptic activation of α2-adrenoceptors, which inhibits sympathetic activity and decreases blood pressure and heart rate.
- Formulation : A white to off-white solid
- λmax: 214 nm
Formula:
C₁₃H₁₆N₂·HCl Peso molecolare: 236,74 g/mol Temperatura di stoccaggio: Refrigerata |
MDL Number:
MFCD12912677 CAS Number: 145108-58-3 |
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