Phosphoramidon
Fornitore: ENZO LIFE SCIENCES
Neprilysin inhibitor
Inhibits neutral endopeptidase 24,11 (NEP, neprilysin; EC 3.4.24.11) (Ki=2 nM), a cell surface zinc metalloprotease which cleaves bioactive peptides such as bradykinin, neurotensin, and enkephalin. Also inhibits neprilysin 2 (Ki~2 nM). Potent inhibitor of endothelin-converting enzyme (ECE) (IC50=0,68 μM).
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