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Anti-CASP7 Mouse Monoclonal Antibody

Fornitore: ENZO LIFE SCIENCES
ADIAAM137C ADIAAM137E
ENZOADIAAM137CEA 174 EUR
ENZOADIAAM137C ENZOADIAAM137E
Anti-CASP7 Mouse Monoclonal Antibody
Anticorpi
The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or executioner caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.

  • For Immunohistochemistry, Western Blot

Recognizes human, mouse, rat, hamster and monkey Caspase-7.

Type: Primary
Antigen: CASP7
Clonality: Monoclonal
Clone:
Conjugation:
Epitope:
Host: Mouse
Isotype:
Reactivity: Human
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