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Anti-CD34 Mouse Monoclonal Antibody (CF640R) [clone: HPCA1/1171]

Fornitore: Biotium
BNC401171-500 BNC401171-100
BNC401171-500EA 560 EUR
BNC401171-500 BNC401171-100
Anti-CD34 Mouse Monoclonal Antibody (CF640R) [clone: HPCA1/1171]
Anticorpi
This antibody recognizes a carbohydrate epitope on a single chain, transmembrane, heavily glycosylated protein of 90-120 kDa, which is identified as CD34 (VI international workshop on human differentiation antigens). Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi's sarcoma, but shows low specificity.

Type: Primary
Antigen: CD34
Clonality: Monoclonal
Clone: HPCA1/1171
Conjugation: CF640R
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human, Rat
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